Project description:The present study examines changes in global gene expression patterns and in virulence factor-associated genes in an extended spectrum beta-lactamase (ESBL)-producing UPEC (ESBL019) during the morphologic transitions induced by an ineffective antibiotic and in the presence of human primary bladder epithelial cells. The morphological shifts induced by ineffective antibiotics are associated with significant transcriptional virulence alterations in ESBL-producing UPEC, which may affect survival and persistence in the urinary tract.
Project description:Dynamics of faecal shedding of Extended Spectrum beta-Lactamase or AmpC-producing Escherichia coli on dairy farms
| PRJEB30024 | ENA
Project description:Genomic characterization of extended-spectrum beta-lactamase-producing and carbapenem-resistant Enterobacteriaceae isolated from urban Wastewater