Project description:To identify genomic evidence of chromosomal instability (CIN) in metastatic (M1) cases, we sampled the same tumor regions for DNA extraction that were previously selected to generate transcriptome data in localized (M0) cases. Since there is limited tissue in PNBX, only 24 cases yielded sufficient quality/quantity of DNA for copy number alteration (CNA) evaluation.

2020-03-26 | GSE147353 | GEO

Thermo Fisher Scientific OncoScan expression array data for undifferentiated uterine sarcomas (expression)

Project description:Thermo Fisher Scientific OncoScan expression array data for undifferentiated uterine sarcoma

2019-08-23 | GSE119041 | GEO

OncoScan analysis of breast carcinomas from the Swedish haemangioma cohort

Project description:The Swedish haemangioma cohort consists of 17,200 women treated with radium-226 for skin haemangioma at an early age (<1.5 years of age) between 1920 and 1965. A total of 877 breast cancer cases were reported by December 2009, estimating an excess relative and absolute risk at the age of 50 years of 0.48 Gy^(−1) and 10.4 (10^4 PYR Gy)^(−1), respectively. We screened 31 primary breast carcinomas for genetic alterations using the OncoScan CNV Plus Assay to assess genomic instability.

2019-04-12 | GSE125700 | GEO

Affymetrix OncoScan FFPE Array array data from Li-Fraumeni Syndrome tumors

Project description:Loss of heterzygosity in TP53 Affymetrix OncoScan FFPE arrays were performed according to the manufacturer's directions on DNA extracted from tumors Copy number analysis of Affymetrix OncoScan FFPE array was performed for two osteosarcoma lung metastases, one lung adenocarcinoma, one meningioma, one pleomorphic sarcoma

2015-02-03 | E-GEOD-64293 | biostudies-arrayexpress