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RNA-sequencing experiments to identify differentially expressed genes between Wild Type and RBM4 KO HAP1 cell line samples

ABSTRACT: RNA-sequencing experiments to identify differentially expressed genes between Wild Type and RBM4 KO HAP1 cell line samples

PROVIDER: PRJNA622500 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11465180_1.fastq.gz	Fastqsanger.gz
	SRR11465180_2.fastq.gz	Fastqsanger.gz
	SRR11465181_1.fastq.gz	Fastqsanger.gz
	SRR11465181_2.fastq.gz	Fastqsanger.gz
	SRR11465182_1.fastq.gz	Fastqsanger.gz

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RNA-sequencing experiments to identify differentially expressed genes between Wild Type and RBM4 KO HAP1 cell line samples

Project description:Here, we implemented a computational pipeline to determine the correlation of expression between individual RBPs and ERVs from single-cell or bulk RNA sequencing data. One of our top candidates for an RBP negatively regulating ERV expression was RNA-Binding Motif Protein 4 (RBM4). This set of bulk RNA-sequencing experiments was performed to identify differentially expressed genes and repetitive elements, particularly HERVs, between independent Wild Type and RBM4 KO clones in the KBM-7 derived, near-haploid human cell line, HAP1

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