Project description:This is genome-scale metabolic model of Saccharomyces cerevisiae as the representative yeast species for the clade Saccharomycetaceae. This model was generated through homology search using a fungal pan-GEM largely based on Yeast8 for Saccharomyces cerevisiae, in addition to manual curation. This model has been produced by the Yeast-Species-GEMs project from Sysbio (www.sysbio.se). This is model version 1.0.0 accompanying the publication (DOI: 10.15252/msb.202110427), currently hosted on BioModels Database (http://www.ebi.ac.uk/biomodels/) and identified by MODEL2109130010. Further curations of this model will be tracked in the GitHub repository: https://github.com/SysBioChalmers/Yeast-Species-GEMs Models for species of the same clade includes: Ashbya aceri; Candida glabrata; Eremothecium coryli; Eremothecium cymbalariae; Eremothecium gossypii; Eremothecium sinecaudum; Kazachstania africana; Kazachstania naganishii; Kluyveromyces lactis; Kluyveromyces marxianus; Lachancea cidri; Lachancea dasiensis; Lachancea fantastica nom. nud.; Lachancea fermentati; Lachancea kluyveri; Lachancea lanzarotensis; Lachancea meyersii; Lachancea mirantina; Lachancea nothofagi; Lachancea quebecensis; Lachancea thermotolerans; Lachancea waltii; Nakaseomyces bacillisporus; Candida bracarensis; Candida castellii; Nakaseomyces delphensis; Candida nivariensis; Naumovozyma castellii; Naumovozyma dairenensis; Saccharomyces arboricola; Saccharomyces cerevisiae; Saccharomyces eubayanus; Saccharomyces kudriavzevii; Saccharomyces mikatae; Saccharomyces paradoxus; Saccharomyces uvarum; Tetrapisispora blattae; Tetrapisispora phaffii; Torulaspora delbrueckii; Vanderwaltozyma polyspora; Zygosaccharomyces bailii; Zygosaccharomyces rouxii; Kazachstania martiniae; Kazachstania unispora; Kazachstania turicensis; Kazachstania bromeliacearum; Kazachstania siamensis; Kazachstania taianensis; Kazachstania intestinalis; Kazachstania rosinii; Kazachstania transvaalensis; Kazachstania spencerorum; Kazachstania viticola; Kazachstania solicola; Kazachstania kunashirensis; Kazachstania aerobia; Kazachstania yakushimaensis; Torulaspora franciscae; Zygotorulaspora mrakii; Kluyveromyces aestuarii; Kluyveromyces dobzhanskii; Zygotorulaspora florentina; Zygosaccharomyces kombuchaensis; Zygosaccharomyces bisporus; Tetrapisispora fleetii; Tetrapisispora iriomotensis; Tetrapisispora namnaonensis; Torulaspora pretoriensis; Yueomyces sinensis; Torulaspora microellipsoides; Torulaspora maleeae. These models are available in the zip file. To cite BioModels, please use: V Chelliah et al; BioModels: ten-year anniversary. Nucleic Acids Res 2015; 43 (D1): D542-D548. To the extent possible under law, all copyright and related or neighbouring rights to this encoded model have been dedicated to the public domain worldwide. Please refer to MIT License for more information.
FROG and miniFROG reports of the models for iPN730 (Lachancea kluyveri) and iSM996 (Kluyveromyces marxianus) also updated.
2024-10-15 | MODEL2109130010 | BioModels
Project description:Genome sequencing of Torulaspora indica and Torulaspora globosa isolates
Project description:Primary objectives: The primary objective is to investigate circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).
Primary endpoints: circulating tumor DNA (ctDNA) via deep sequencing for mutation detection and by whole genome sequencing for copy number analyses before start (baseline) with regorafenib and at defined time points during administration of regorafenib for treatment efficacy in colorectal cancer patients in terms of overall survival (OS).