Project description:To reveal the altered expression profiles of circular RNAs (circRNAs) in the peripheral blood mononuclear cells (PBMCs) of patients with retinopathy of prematurity (ROP), microarray analysis was conducted in the samples from ROP patients and controls.

2022-08-10 | GSE204780 | GEO

Epithelial membrane protein-2 promotes VEGF signaling to promote pathological neovascular growth in retinopathy of prematurity

Project description:Retinopathy of prematurity (ROP) is a leading cause of childhood blindness, and exclusively affects infants born prematurely. In this study, we test the hypothesis that EMP2 contributes to neovascularization in a mouse model of the disease. We show that EMP2 promotes neuronal VEGF signaling and that its downregulation reduces severity of neovascularization.

2021-12-17 | GSE123945 | GEO

GENEVA GWAS of Prematurity and its Complications - European Ancestry

Project description:GENEVA GWAS of Prematurity and its Complications - European Ancestry

| PRJNA75461 | ENA

GENEVA GWAS of Prematurity and its Complications - African Ancestry

Project description:GENEVA GWAS of Prematurity and its Complications - African Ancestry

| PRJNA75465 | ENA

Placental Inflammation Significantly Correlates with Reduced Risk for Retinopathy of Prematurity

Project description:Placental Inflammation Significantly Correlates with Reduced Risk for Retinopathy of Prematurity

| PRJNA901967 | ENA

Project description:Clinical and genetic analysis of retinopathy of prematurity

| PRJNA623135 | ENA

Gene expression microarray analysis of early oxygen-induced retinopathy (OIR)

Project description:Different inbred strains of rats differ in their susceptibility to OIR, an animal model of human retinopathy of prematurity. We examined gene expression profiles in Fischer 344 (F344, resistant to OIR) and Sprague Dawley (SD, susceptible to OIR) rats at the early time point of day 3 to identifying gene pathways related to the underlying genetic cause of phenotypic differences between strains.

2009-11-13 | GSE18998 | GEO

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