Project description:Good quality standard adult blood samples and cord blood samples hybridized to the Illumina Infinium HumanMethylation450 BeadChip and used as methylation controls.
Project description:Cord blood DNA methylation is associated with numerous health outcomes and environmental exposures. Whole cord blood DNA reflects all nucleated blood cell types, while centrifuging whole blood separates red blood cells by generating a white blood cell buffy coat. Both sample types are used in DNA methylation studies. Cell types have unique methylation patterns and processing can impact cell distributions, which may influence comparability. To evaluate differences in cell composition and DNA methylation between buffy coat and whole cord blood samples, cord blood DNA methylation was measured with the Infinium EPIC BeadChip (Illumina) in 8 individuals, each contributing buffy coat and whole blood samples.
Project description:DNA methylation profiling of placenta and cord blood samples. The Illumina GoldenGate methylation assay was used to obtain DNA methylation profiles across approximately 1,536 CpGs in 23 placenta and 23 cord blood samples.
Project description:Genome wide DNA methylation profiling of cord blood samples from 48 newborns. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs.
Project description:Genome wide DNA methylation profiling of cord blood cells obtained from gestational diabetes mellitus (GDM) pregnancies. The Illumina EPIC methylation beadchip array was used to obtain DNA methylation profiles across approximately 850,000 CpG dinucleotide methylation loci in DNA isolated from cord blood. Samples include 165 GDM subjects.
Project description:DNA methylation profiling of placenta and cord blood samples. The Illumina GoldenGate methylation assay was used to obtain DNA methylation profiles across approximately 1,536 CpGs in 23 placenta and 23 cord blood samples. Bisulphite converted DNA from the 46 samples were hybridised to the Illumina GoldenGate Methylation assay
Project description:Genome wide DNA methylation profiling of cord blood cells obtained from normal glucose tolerance (NGT) pregnancies. The Illumina EPIC methylation beadchip array was used to obtain DNA methylation profiles across approximately 850,000 CpG dinucleotide methylation loci in DNA isolated from cord blood. Samples include 61 NGT subjects.
Project description:Genome wide DNA methylation profiling of placenta/cord blood/saliva samples obtained from babies born by oocyte in vitro maturation (IVM) or in vitro fertilization (IVF). The Illumina Infinium EPIC Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 850,000 CpGs. The main goal of this project was to find specific methylation profiles associated to use of IVM.
Project description:Genome wide DNA methylation profiling of CHAMACOS cord blood. The Illumina Infinium 450k Human DNA methylation Beadchip was used to obtain DNA methylation profiles across approximately 450,000 CpGs. Methylation was assessed in 380 cord blood samples of members of the CHAMACOS cohort.
Project description:Genome wide DNA methylation profiling of cord blood samples from 48 newborns. The Illumina Infinium 27k Human DNA methylation Beadchip v1.2 was used to obtain DNA methylation profiles across approximately 27,000 CpGs. Bisulphite converted DNA from the 48 samples were hybridised to the Illumina Infinium 27k Human Methylation Beadchip v1.2