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MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages

ABSTRACT: MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages

PROVIDER: PRJNA630260 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR11685268_1.fastq.gz	Fastqsanger.gz
	SRR11685268_2.fastq.gz	Fastqsanger.gz
	SRR11685269_1.fastq.gz	Fastqsanger.gz
	SRR11685269_2.fastq.gz	Fastqsanger.gz
	SRR11685270_1.fastq.gz	Fastqsanger.gz

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MiR-26a targets EphA2 to resist intracellular Listeria monocytogenes in macrophages

Project description:We performed transcriptome analyses of miR-26a-overexpressing RAW264.7 cells (RAW264.7.miR-26a.OE) and NC-plasmid-transfected RAW264.7 cells (RAW264.7.NC), using RNA-seq . We identified 121 genes that were downregulated in RAW264.7.miR-26a.OE cells compared with RAW264.7.NC cells. Among the downregulated genes, we identified four putative target genes, using TargetScan (www.targetscan.org), including EphA2, Map3k9, Nhsl1, and Otud1, which all contain a putative miR-26a seed sequence.

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