Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

An activity-mediated transition in transcription in early postnatal neurons

ABSTRACT: An activity-mediated transition in transcription in early postnatal neurons

PROVIDER: PRJNA632670 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11787600.fastq.gz	Fastqsanger.gz
	SRR11787700.fastq.gz	Fastqsanger.gz
	SRR11787601.fastq.gz	Fastqsanger.gz
	SRR11787701.fastq.gz	Fastqsanger.gz
	SRR11787602.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 281

Similar Datasets

An activity-mediated transition in transcription in early postnatal neurons [10X]

Project description:An activity-mediated transition in transcription in early postnatal neurons [10X]

| PRJNA632676 | ENA

An activity-mediated transition in transcription in early postnatal neurons [HiChIP]

Project description:An activity-mediated transition in transcription in early postnatal neurons [HiChIP]

| PRJNA632675 | ENA

An activity-mediated transition in transcription in early postnatal neurons [ATAC-seq]

Project description:An activity-mediated transition in transcription in early postnatal neurons [ATAC-seq]

| PRJNA632672 | ENA

An activity-mediated transition in transcription in early postnatal neurons [RNA-seq]

Project description:An activity-mediated transition in transcription in early postnatal neurons [RNA-seq]

| PRJNA632674 | ENA

An activity-mediated transition in transcription in early postnatal neurons [ChIP-seq]

Project description:An activity-mediated transition in transcription in early postnatal neurons [ChIP-seq]

| PRJNA632671 | ENA

An activity-mediated transition in transcription in early postnatal neurons [Cut&Run]

Project description:An activity-mediated transition in transcription in early postnatal neurons [Cut&Run]

| PRJNA632677 | ENA

An activity-mediated transition in transcription in early postnatal neurons [BS-seq]

Project description:An activity-mediated transition in transcription in early postnatal neurons [BS-seq]

| PRJNA632673 | ENA

An activity-mediated transition in transcription in early postnatal neurons [10X]

Project description:The maturation of the mammalian brain occurs after birth, and this stage of neuronal development is frequently impaired in neurological disorders, such as autism and schizophrenia. However, the mechanisms that regulate postnatal brain maturation are poorly defined. By purifying neuronal subpopulations across brain development in mice, we identify a postnatal switch in the transcriptional regulatory circuits that operates in the maturing mammalian brain. We show that this developmental transition includes the formation of hundreds of cell-type-specific neuronal enhancers in the postnatal period that might in part be modulated by neuronal activity. Once selected, these enhancers are active throughout adulthood, suggesting that their formation in early life shapes neuronal identity and regulates mature brain function.

2020-06-25 | GSE150537 | GEO

An activity-mediated transition in transcription in early postnatal neurons [HiChIP]

2020-06-25 | GSE150536 | GEO

An activity-mediated transition in transcription in early postnatal neurons [RNA-seq]

2020-06-25 | GSE150535 | GEO