Project description:The potential mechanism of ZX-7101 against influenza viruses is unknown. In this study, Transcriptome analysis demonstrated that ZX-7101 could directly inhibit viral replication and therefore affected the expression of genes involved in inflammation and the cell cycle.
Project description:MLS000408882-01 and MLS000573813-01 were identified through a cell based screen that measures the reactivation of an epigenetically silenced transgene. MLS000408882-01 and MLS000573813-01 shows selectivity for cancer vs. normal cells affecting both transcriptional patterns and cell viability in a cancer specific manner.