Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Homo sapiens

ABSTRACT: High throughput RNA sequencing identifies breast cancer circular RNAs

PROVIDER: PRJNA637187 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR11939854_1.fastq.gz	Fastqsanger.gz
	SRR11939854_2.fastq.gz	Fastqsanger.gz
	SRR11939855_1.fastq.gz	Fastqsanger.gz
	SRR11939855_2.fastq.gz	Fastqsanger.gz
	SRR11939856_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 20

Similar Datasets

Identify and characterize the circular RNAs expressed in lactating rat mammary glands

Project description:Purpose: A novel member of RNAs, circular RNAs (circRNAs), has recently been evidenced to play key role on biological process regulation. However, the global landscape of circular RNA remains largely unknown. In the present study, deep RNA-sequencing technique was employed to identify and characterize the circular RNAs expressed in lactating rat mammary gland.compare NGS-derived retinal transcriptome profiling (RNA-seq) to microarray and quantitative reverse transcription polymerase chain reaction (qRT–PCR) methods and to evaluate protocols for optimal high-throughput data analysis Methods:Deep RNA-sequencing technique was employed Results: A total of 6824 and 4523 circRNAs were identified from rat mammary glands at two lactation stages, respectively. Numerous circRNAs seem to be specifically expressed in different lactation stages, as only 1314 circRNAs were detected in both libraries. Majority of the candidate circRNAs maps to intronic and intergenic regions, namely noncoding regions. There existed the circular preference or specificity of some genes. Interestingly, 4 protein coding genes (Rev3l, IGSF11, MAML2, and LPP) that also tanscripted high level circRNAs have been reported to be involved in cancer. The distribution of specific miRNA binding sites and RNA binding proteins binding sites also implied the role of circRNAs in mammary gland development and tumorigenesis. Conclusions:The results provide the basis for comparisons with breast cancer profiles and for selection of representative circRNA candidates for future functional characterization in breast development and breast cancer.

2017-08-20 | GSE60539 | GEO

Homo sapiens

Project description:High-throughput RNA sequencing on circular RNA profiles of human bladder cancer tissues and normal bladder tissues

| PRJNA381054 | ENA

Homo sapiens whole blood.

Project description:RNA extracted at 240min. Samples are rRNA depleted. Expression measurement of Homo sapiens genes.

2019-07-31 | GSE114179 | GEO

Homo sapiens

Project description:Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [cervical_cancer_circRNA]

| PRJNA355651 | ENA

Homo sapiens

Project description:Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [cervical_cancer_mRNA]

| PRJNA355650 | ENA

Homo sapiens

Project description:Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [Plasma_circRNA]

| PRJNA355649 | ENA

Homo sapiens

Project description:Circular RNAs are super abundant in cervical tumor and plasma detected by high throughput microarray [standard_RNA_circRNA]

| PRJNA355648 | ENA

Homo sapiens

Project description:Expression profiles of circular RNAs in bladder cancer