Project description:DES is a synthetic estrogen that is associated with adverse effects on reproductive organs. Our group has employed estrogen receptor (ER) α knockout (αERKO) mice to gain insight into the contribution of ER-dependent pathways in mediating the effects of neonatal DES exposure in female and male reproductive tract tissues. The objective of this study is to compare gene expression profiles between the WT-veh and -DES groups or αERKO-veh and -DES from the adult male mice (week 10) of the SV tissues to identify differential genes.

2018-03-27 | GSE95314 | GEO

RNA-Seq and H3K27ac ChIP-Seq in the mouse seminal vesicles (SVs) and uterus (U) following neonatal DES exposure

Project description:This SuperSeries is composed of the SubSeries listed below.

2023-06-14 | GSE152526 | GEO

Murine Müllrian duct Day0 DES

Project description:Diethylstilbestrol (DES) inhibits the differentiation of female reproductive tracts during fetal and neonatal days . We examined global gene expressions in the oviduct, uterus and vagina in newborn mice with or without DES. These results suggest understanding the mechanism of the differentiation of female reproductive tracts. Keywords: ordered

2004-10-28 | GSE1886 | GEO

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