Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Global regulators fine-tune the translation and metabolic machinery in Escherichia coli under proteome-efficient anaerobic fermentation

ABSTRACT: Global regulators fine-tune the translation and metabolic machinery in Escherichia coli under proteome-efficient anaerobic fermentation

PROVIDER: PRJNA644510 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12162081_1.fastq.gz	Fastqsanger.gz
	SRR12162081_2.fastq.gz	Fastqsanger.gz
	SRR12162082_1.fastq.gz	Fastqsanger.gz
	SRR12162082_2.fastq.gz	Fastqsanger.gz
	SRR12162083_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Global regulators fine-tune the translation and metabolic machinery in Escherichia coli under proteome-efficient anaerobic fermentation

Project description:We report high-throughput RNA sequencing of WT, Δfnr, ΔarcA and Δihf in the exponential phase under anaerobic fermentative conditions

2021-02-28 | GSE153906 | GEO

H3K4me3/H3K27me3 bivalent chromatin function to fine-tune gene expression level

Project description:H3K4me3/H3K27me3 bivalent chromatin function to fine-tune gene expression level

| PRJNA428482 | ENA

A m6A methyltransferase fine-tune m6A modification and ubiquitination to balance antiviral immunity and yield

Project description:Posttranscriptional and posttranslational modifications play crucial roles in plant immunity. However, how plant fine-tune these two modifications to activate antiviral immunity remains unknown. Here, we report that the m6A methyltransferase TaHAKAI is utilized by wheat yellow mosaic virus (WYMV) to increase viral genomic m6A modification and promotes viral replication. However, TaHAKAI also functions as an E3 ligase that targets the viral RNA silencing suppressor P2 for degradation and inhibits viral infection. A major allele of TaHAKAI in susceptible cultivar reduced the E3 ligase activity but not m6A methyltransferase activity, promoting viral infection. Interestingly, TaHAKAIR attenuates the mRNA stability of TaWPS1, the negative regulator of spike development, to increase panicle length and spikelet number by modulating its m6A modification. Our study reveals a new mechanisms of balancing disease resistance and yield by fine-tuning m6A modification and ubiquitination.

2024-10-09 | PXD056650 | Pride

Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin by biotinylated transposon (293T)

Project description:This study introduced a method for directly identifying the transcriptional machinery on accessible chromatin (ATAC-MS) in a proteome scale. The goals of this study are to integrate ATAC-seq with ATAC-MS to investigate the real-time in vivo transcriptional regulatory processes in organisms.

2024-01-16 | GSE138855 | GEO

Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin by biotinylated transposon [fractionation]

2024-01-16 | GSE164299 | GEO

Low-level repressive histone marks fine-tune stemness gene transcription in neural stem cells [scRNA-seq]

Project description:Coordinated regulation of stemness gene activity by transcriptional and translational controls poise stem cells for a timely cell-state transition during differentiation. Although important for all stemness-to-differentiation transitions, mechanistic understanding of the fine-tuning of stemness gene transcription is lacking due to the compensatory effect of translational control. We used intermediate neural progenitor (INP) identity commitment to define the mechanisms that fine-tune stemness gene transcription in fly neural stem cells (neuroblasts). We demonstrate that the transcription factor FruitlessC (FruC) binds cis-regulatory elements of most genes uniquely transcribed in neuroblasts. Loss of fruC function alone has no effect on INP commitment but drives INP dedifferentiation when translational control is reduced. FruC negatively regulates gene expression by promoting low-level enrichment of the repressive histone mark H3K27me3 in gene cis-regulatory regions. Identical to fruC loss-of-function, reducing Polycomb Repressive Complex 2 activity increases stemness gene activity. We propose low-level H3K27me3 enrichment fine-tunes stemness gene transcription in stem cells, a mechanism likely conserved from flies to humans.

2023-06-23 | GSE218255 | GEO

Low-level repressive histone marks fine-tune stemness gene transcription in neural stem cells [CUT&Tag]

2023-06-23 | GSE218253 | GEO

Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin with biotinylated transposons [ATAC-seq]

2024-01-16 | GSE180398 | GEO

Proteome-wide profiling of Transcriptional Machinery on Accessible Chromatin with biotinylated transposons [ChIP-Seq]

2024-01-16 | GSE175575 | GEO