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The effects of Korean Red Ginseng on Di-(2-ethylhexyl) phthalate-induced inflammatory response in endometrial cancer cells

ABSTRACT: The effects of Korean Red Ginseng on Di-(2-ethylhexyl) phthalate-induced inflammatory response in endometrial cancer cells

PROVIDER: PRJNA646121 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12215091.fastq.gz	Fastqsanger.gz
	SRR12215092.fastq.gz	Fastqsanger.gz
	SRR12215093.fastq.gz	Fastqsanger.gz

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The effects of Korean Red Ginseng on Di-(2-ethylhexyl) phthalate-induced inflammatory response in endometrial cancer cells

Project description:Di-(2-ethylhexyl) phthalate (DEHP) is the most common endocrine disrupting chemical used as a plasticizer. DEHP is associated with the development of endometrium-related diseases through the induction of inflammation. The major therapeutic approaches against endometrial cancer and endometriosis involve the suppression of inflammatory response. Korean red ginseng (KRG) is a natural product with anti-inflammatory and anti-carcinogenic effects. Thus, the purpose of this study is to investigate the effects of KRG on DEHP-induced inflammatory response in endometrial cancer Ishikawa cells.

2022-07-13 | GSE154388 | GEO

Green tea polyphenols alleviate liver injury induced by di(2-ethylhexyl) phthalate in mice

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Systems biology analysis of Korean red ginseng effects on Immobilization stressed mice brain

Project description:Here we present molecular mechanisms of Korean red ginseng (KRG) on immobilization stresses Keywords: stress response Mice were divided into three groups (3 mice / group): control, stress + no treat, and stress + Korean Red Ginseng (KRG, 100 mg). Stress + KRG group were given KRG 100 mg orally for 7 days and then exposed to immobilization stress for 45 min. stress + no treat group were administrated with phosphate buffer saline (d-PBS, pH 7.4) together with IMO stress for 45 min.

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Long term evaluation of biological effects of Korean Red Ginseng in rat serum

Project description:This study investigated the safety and efficacy of 12-mo administration of Korean Red Ginseng.

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Expression data from HeLa cell treated with Bisphenol S and Mono-ethylhexyl phthalate

Project description:Bisphenol S and mono-ethylhexyl phthalate are widely used in the industry of making plastic, mailing envelopes, tickets, etc. Humans are exposed to these compounds by skin contact, inhalation, and food ingestions. However, the molecular mechanisms of these compounds' adverse effects are still unclear. We address the molecular and cellular mechanisms underlying Bisphenol S and mono-ethylhexyl phthalate effects on HeLa cells. Here microarray analysis was performed to identify distinct classes of up- or down-regulated genes and their connections to the different metabolic pathways.

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Exposure to di(2-ethylhexyl) phthalate and diisononyl phthalate during adulthood disrupts hormones and ovarian folliculogenesis throughout the prime reproductive life of the female mouse.

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