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Transcriptomic analysis of mice heart following transverse aortic constriction (TAC) surgery

ABSTRACT: Transcriptomic analysis of mice heart following transverse aortic constriction (TAC) surgery

PROVIDER: PRJNA655620 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12398825.fastq.gz	Fastqsanger.gz
	SRR12398826.fastq.gz	Fastqsanger.gz
	SRR12398827.fastq.gz	Fastqsanger.gz
	SRR12398828.fastq.gz	Fastqsanger.gz
	SRR12398829.fastq.gz	Fastqsanger.gz

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Expression data from mouse heart post transverse aortic constriction (TAC) -surgery 2 weeks

Project description:Expression data from mouse heart post transverse aortic constriction (TAC) -surgery 2 weeks

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Project description:In order to investigate the differentially expressed genes in Acsl4 knockout after TAC (Transverse aortic constriction) or sham surgery. The experiment was divided to four groups including sham-operated Acsl4 flox/flox mice (FS), sham-operated Acsl4 knockout mice (KS), TAC-operated Acsl4 flox/flox mice (FT), TAC-operated Acsl4 knockout mice (KT) n=3 mice/group. The heart tissue was isolated after 21 days after performing TAC or sham surgery.

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Transcription profiling of hearts from FVB male mice subjected to cardiac pressure overload by transverse aortic constriction to study the quantitative relationships between gene expression and left ventricular hypertrophy

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Transcription profiling of mouse gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 2, 10 and 21 days to identify the differential expression of genes

Project description:Microarray analysis of gene expression after transverse aortic constriction in mice: comparison of TAC vs. sham group at 48 hours, 10 days, and 3 weeks.

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Project description:We did TAC surgery for mice and daily treated the mice with Vehicle or SR9009

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ACAA2 genome-binding patterns before and after transverse aortic constriction in C57Bl/6J mice on different diets [ACAA2]

Project description:Acetyl-CoA acyltransferace 2 (ACAA2) associates with chromatin at promoter sites in the heart of C57Bl/6J mice. A high-fat vs. low-fat diet reduces it promoter abundance, whereas, transverse aortic constriction (TAC) increases it slight.

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Project description:We employed the Affymetrix GeneChip technology to evaluate the patterns of expression in two different in vivo models of cardiac remodeling and in two different regions (left ventricle free wall and septum) of the heart. Mice underwent transverse aortic constriction (TAC); myocardial infarction (MI) or Sham operation and RNA from the left ventricle free wall and the septum was isolated 1 week later.

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Expression data from mouse heart post transverse aortic constriction (TAC) -surgery 2 weeks

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2015-06-21 | E-MTAB-2732 | biostudies-arrayexpress

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