Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The FASTK family proteins are master regulators in mitochondrial RNA processing

ABSTRACT: The FASTK family proteins are master regulators in mitochondrial RNA processing

PROVIDER: PRJNA658336 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12483652.fastq.gz	Fastqsanger.gz
	SRR12483653.fastq.gz	Fastqsanger.gz
	SRR12483654.fastq.gz	Fastqsanger.gz
	SRR12483655.fastq.gz	Fastqsanger.gz
	SRR12483656.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 6

Similar Datasets

The FASTK family proteins are master regulators in mitochondrial RNA processing

Project description:Investigation of roles of the FASTK protein family in non-canonical mitochondrial RNA processing

2021-10-19 | GSE156556 | GEO

The FASTK family proteins are master regulators in mitochondrial RNA processing

Project description:The FASTK family proteins are emerging key post-transcriptional regulators in mitochondrial gene expression. In attempts to uncover their molecular functions, we carried out BioID experiments to identify proteins interacting with FASTKD4 and FASTKD5. Our data suggest that both proteins have similar protein interactome profiles, highlighting their roles in mitochondrial RNA processing.

2021-11-02 | PXD020993 | Pride

Rb family proteins are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

Project description:Rb family proteins are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

| PRJNA788447 | ENA

Rb family proteins and Activator E2F family transcription factors are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

Project description:Rb family proteins and Activator E2F family transcription factors are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

| PRJNA788441 | ENA

Rb family proteins are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

Project description:The long-term maintenance of the adult neurogenic niche and neurogenesis is dependent on the proper regulation of entry and exit from quiescence. The dynamic transition from quiescence to activation is a complex process requiring not only precise cell cycle control, but also a co-ordinated phenotypic transition involving transcriptional and morphological changes. Presently, the mechanisms by which such a complex repertoire of factors interact and co-ordinate with the core cell cycle machinery to mediate these critical NSC fate transitions remains unknown. Here we show that the Rb/E2F axis functions as an on-off switch for NSC quiescence and activation, by linking the cell cycle machinery to pivotal regulators of NSC fate. Compound deletion of Rb family proteins results in massive activation and expansion of NSCs, and induces a global transcriptomic transition towards NSC activation followed by niche depletion. Deletion of their target activator E2Fs1/3 results in the failure of NSCs to become activated and the acquisition of a global transcriptome associated with intractable NSC quiescence and the cessation of adult neurogenesis. We further show that the Rb/E2F axis orchestrates these fate transitions through the direct regulation of factors essential to NSC function, including REST and ASCL1. This places the Rb/E2F axis as a master regulator of NSC fate, coordinating cell cycle control with NSC activation and quiescence fate transitions.

2022-11-01 | GSE190765 | GEO

Highly-conserved regulatory activity of the ANR family in the virulence of diarrheagenic bacteria through interaction with Master and Global regulators

Project description:Highly-conserved regulatory activity of the ANR family in the virulence of diarrheagenic bacteria through interaction with Master and Global regulators

| PRJNA936843 | ENA

ChIP-seq of biofilm master regulators in four species of Candida

Project description:ChIP-seq of biofilm master regulators in four species of Candida

| PRJNA675631 | ENA

P-stalk ribosomes act as master regulators of cytokine-mediated processes

Project description:P-stalk ribosomes act as master regulators of cytokine-mediated processes

| PRJNA957309 | ENA

ChIP-seq of biofilm master regulators in four species of Candida

Project description:The purpose of this experiment was to identify the genes bound by the biofilm master regulators (Bcr1, Brg1, Efg1, Ndt80, Rob1 and Tec2) in Candida albicans, C. dubliniensis, C. tropicalis and C. parapsilosis during biofilm formation. The regulators were tagged with a c-myc epitope and the immunoprecipitation of the tagged strain was compared to that of an untagged control strain.

2021-04-14 | GSE161133 | GEO

Activator E2F family transcription factors are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

Project description:Activator E2F family transcription factors are master regulators of the molecular signatures instructing the quiescent and activated adult neural stem cell state

| PRJNA788446 | ENA

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data