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RALY selectively regulates the alternative splicing of transcription factors and the expression of immune/ inflammatory response genes in HeLa cells

ABSTRACT: RALY selectively regulates the alternative splicing of transcription factors and the expression of immune/ inflammatory response genes in HeLa cells

PROVIDER: PRJNA660180 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12546011_1.fastq.gz	Fastqsanger.gz
	SRR12546011_2.fastq.gz	Fastqsanger.gz
	SRR12546012_1.fastq.gz	Fastqsanger.gz
	SRR12546012_2.fastq.gz	Fastqsanger.gz
	SRR12546013_1.fastq.gz	Fastqsanger.gz

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RALY selectively regulates the alternative splicing of transcription factors and the expression of immune/ inflammatory response genes in HeLa cells

Project description:We applied a HeLa cell model with enforced expression of RALY and studied the effect of RALY on cancer cell proliferation and apoptosis. We then obtained RNA-seq transcriptomes from the normal cells and those with RALY overexpression, followed by analysis of the deregulation of alternative splicing and gene expression that were mediated by RALY overexpression.

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