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BMPR2 Regulates Hypoxic Exosome Signaling to Maintain Vascular Homeostasis

ABSTRACT: BMPR2 Regulates Hypoxic Exosome Signaling to Maintain Vascular Homeostasis

PROVIDER: PRJNA660478 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR12558739_1.fastq.gz	Fastqsanger.gz
	SRR12558739_2.fastq.gz	Fastqsanger.gz
	SRR12558740_1.fastq.gz	Fastqsanger.gz
	SRR12558740_2.fastq.gz	Fastqsanger.gz
	SRR12558741_1.fastq.gz	Fastqsanger.gz

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BMPR2 Regulates Hypoxic Exosome Signaling to Maintain Vascular Homeostasis

Project description:Endothelial cells (EC) sense stimuli in the circulation and release responsive signaling molecules to coordinate the multicellular adaptations required to maintain vascular homeostasis. The goal of this study were to analyze the transcriptional changes induced by hypoxia in control donor pulmonary arterial endothelial cells and the effect of loss of BMPR2 that is associated with pulmonary arterial hypertension.

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BMPR2 Regulates Hypoxic Extracellular Vesicle Signaling to Maintain Vascular Homeostasis.

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