Project description:ATAC-seq was used to locate putative enhancer regions in the early development (tailbud stage), developing male and female gonads of the marine chrodate Oikopleura dioica.
Project description:Under crowded, nutrient-limiting conditions, growth in the marine chordate O. dioica arrests until favorable conditions return. We profiled translation genome-wide using ribosome profiling in O. dioica during growth arrest and growth arrest recovery. We found that initial recovery is independent of nutrient-responsive, trans-spliced genes, suggesting that animal density is the primary trigger for the resumption of development in this species.