Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

PolyA RNA sequencing of P7 HMGCS2 KO and WT liver

ABSTRACT: PolyA RNA sequencing of P7 HMGCS2 KO and WT liver

PROVIDER: PRJNA666698 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12749703.fastq.gz	Fastqsanger.gz
	SRR12749704.fastq.gz	Fastqsanger.gz
	SRR12749705.fastq.gz	Fastqsanger.gz
	SRR12749706.fastq.gz	Fastqsanger.gz
	SRR12749707.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

PolyA RNA sequencing of P7 HMGCS2 KO and WT liver

Project description:To assess the impact of neonatal insuficient ketogenesis, RNA-seq analysis of P7 livers were performed.

2020-10-01 | GSE158853 | GEO

Expression data from P7 and adult wt and Tenascin-R (Tnr) deficient mice brain

Project description:We used the microarray to investigate the lack of Tenascin-R in brain of adult and P7 mice. The aim was to find differential expressed genes which could explain the behaviour differences between the tenascin wt and ko mice. The data show that not many genes are dysregulated in the Tnr deficient mouse in comparison to the wt mouse brain. Gas5 was one of the dysregulated genes. Gas5 was dysregulated in the P7 and 2 month old mice.

2009-12-15 | GSE19454 | GEO

Transcription profiling of mouse P7 and adult wt and Tenascin-R (Tnr) deficient mice brain

2009-12-19 | E-GEOD-19454 | biostudies-arrayexpress

Liver samples from WT and Atg7 liver specific KO mice

Project description:iTRAQ proteomics was performed for Liver samples from WT and Atg7 liver specific KO mice

2023-07-20 | PXD043936 |

Dicer WT/KO MSC RNA-Seq [polyA RNA]

Project description:RNA-Seq performed on Dicer KO and WT murine mesenchymal stem cells MicroRNAs (miRNAs) are small non-coding RNAs that regulates development and disease but induce only moderate repression of directs mRNA targets, suggesting that they coordinate with other modes ofs cellular regulation to effect large changes in gene expression. Ins this work we decouple direct effects of global miRNA loss froms transcriptional changes downstream in a pair of isogenic murines fibroblast cell lines with and without Dicer expression. Wes demonstrate how effects on direct miRNA targets are amplified bys transcription machinery through the construction of a network models that identifies specific transcription factors that cause changes ins mRNA expression upon Dicer loss. Through transcription factors over-expression, we delineate miRNA-mediated transcriptional programss and identify miRNA-mediated coherent and incoherent feed-forwards loops, suggesting a functional role of the interaction between miRNAss and transcription factors. In total, our results indicate thats miRNAs tightly control transcription factors within a denses interconnected network to modulate gene expression. Examination of mature mRNA expression changes in adult mesenchymal stem cells (immortalized monoclonal lines of murine MSCs) with and without Dicer (WT: Dicer f/f, KO: Dicer -/-).

2014-11-17 | E-GEOD-61031 | biostudies-arrayexpress

Transcriptome analysis of WT and ATRX KO Cast x 129 mouse ES cells

Project description:Analysis of gene expression in WT and ATRX KO Cast x 129 Mouse ES cells Paired end RNA-seq analysis of PolyA selected RNA and PolyA depeleted RNA from in both wildtype nd ATRX knocked out Castx129 Mouse ES Cells

2015-04-16 | E-GEOD-59269 | biostudies-arrayexpress

Comparison of total and polyribosome-associated mRNA levels in male Fmr1 KO mice and male WT littermates

Project description:The Fragile X Mental Retardation Protein, FMRP, is thought to regulate the translation of a specific set of neuronal mRNAs on polyribosomes. Therefore, we prepared polyribosomes on sucrose gradients and purified mRNA specifically from these fractions, as well as the total mRNA levels, to determine whether a set of mRNAs might be changed in its % association with polyribosomes in the absence of FMRP in the KO mouse model. No significant differences were found, other than the Fmr1 transcript itself, in total mRNA levels or % polyribosome association that withstood multiple test correction, in P7 Fmr1 KO mouse cerebral cortex compared with WT littermates.. We prepared polyribosomes on sucrose gradients from 6 littermate pairs of Fmr1 KO and WT littermates (FVB background, P7 males, cerebral cortex) and purified RNA from both polyribosomal fractions and input to the gradient, reflecting total mRNA levels for comparison.

2011-07-20 | E-GEOD-26745 | biostudies-arrayexpress

Changes in gene expression and RNA editing in Adar2-WT and Adar2-KO Mouse embryonic Fibroblasts (MEFs)

Project description:Purpose: Measure gene expression and RNA editing changes in Adar-WT and Adar2-KO MEFs Methods: Performed PolyA+ RNA-seq (single end, one sample each) of Adar2-WT and Adar2-KO MEFs Results: Observed changes in editing and gene expression of several genes Conclusion: Adar2 influences gene expression and editing of transcripts

2016-12-23 | GSE74746 | GEO

Whole esophagi of WT, Nrf2-/- and Keap1-/- mice on C57BL background at E11.5, E15.5, P0 and P7, and esophageal epithelium of adult (8 weeks old) mice

Project description:Transcriptional profiling of mouse esophageal development. Goal was to globally profile critical genes and signaling pathways during the development of mouse esophagus and determine how Nrf2/Keap1 pathway regulates the morphogenesis of the esophageal epithelium. Mutiple-comparison. WT-E11.5 vs. WT-E15.5 vs. WT-P0 vs. WT-P7; WT-P7 vs. WT-adult; WT-adult vs. Nrf2-/--adult; WT-P7 vs. Nrf2-/--P7 vs. Keap1-/--P7 vs. Nrf2-/-Keap1-/--P7. Biological replicates: 3 replicates for each group.

2011-12-09 | E-GEOD-34278 | biostudies-arrayexpress

WT and ATRX KO

Project description:WT and ATRX KO

| PRJNA254835 | ENA