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Gene expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

ABSTRACT: Gene expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

PROVIDER: PRJNA670019 | ENA |

REPOSITORIES: ENA

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miRNA expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

Project description:miRNA expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

| PRJNA670020 | ENA

miRNA expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

Project description:The roles of miRNA in osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) remain largely unexplored. In this study, the underlying molecular mechanism of osteogenic differentiation in hPDLSCs is investigated using microarray profiling.

2020-10-19 | GSE159508 | GEO

Gene expression profifile during osteogenic differentiation of hPDLSCs was analyzed using microarray

Project description:The roles of lncRNAs and mRNAs in osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) remain largely unexplored. In this study, the underlying molecular mechanism of osteogenic differentiation in hPDLSCs is investigated using microarray profiling.

2020-10-19 | GSE159507 | GEO

Gene expression profile during odontogenic differentiation was analyzed using a microarray (lncRNA).

Project description:Gene expression profile during odontogenic differentiation was analyzed using a microarray (lncRNA).

| PRJNA574990 | ENA

Gene expression profile during odontogenic differentiation was analyzed using a microarray (miRNA).

Project description:Gene expression profile during odontogenic differentiation was analyzed using a microarray (miRNA).

| PRJNA574991 | ENA

Gene expression profile during odontogenic differentiation was analyzed using a microarray (miRNA).

Project description:The roles of microRNAs (miRNAs) in odontogenic differentiation of human dental pulp stem cells (hDPSCs) remain largely unexplored. In this study, the underlying molecular mechanism of osteogenic differentiation in hDPSCs is investigated using miRNA profifiling.

2019-10-01 | GSE138180 | GEO

Gene expression profile during odontogenic differentiation was analyzed using a microarray (lncRNA).

Project description:The roles of lncRNAs and mRNAs in odontogenic differentiation of human dental pulp stem cells (hDPSCs) remain largely unexplored. In this study, the underlying molecular mechanism of osteogenic differentiation in hDPSCs is investigated using miRNA profifiling.

2019-10-01 | GSE138179 | GEO

Sexual dimorphism in osteogenic differentiation

Project description:Sexual dimorphism in osteogenic differentiation

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Osteogenic differentiation-related miRNA expression profile of human mesenchymal stem cells

Project description:Mesenchymal stem cells (MSCs) are the multipotent stem cells of adult human tissues that have the ability to replicate with high proliferative rates and are responsible for the tissue renewal and regeneration. Effective osteogenic differentiation of adipose-derived stem cells (ADSCs) encourages clinical application of the cells in bone regeneration. Regeneration of damaged joints is highly dependent on the presence of MSC in synovia. Synovial membrane-derived MSCs (SM-MSCs) show good multi-lineage differentiation potential, low degree of invasiveness, and are considered as an alternative treatment strategy for arthritis-damaged tissues. Studies in MSCs from different sources identified several miRNAs important for osteogenesis. Less is known about the participation of particular miRNAs in osteogenic differentiation of SM-MSCs, the potential source of MSCs for authologous cell therapy in arthritis. In the present study, the changes in miRNA expression profile occurring during osteogenic differentiation were analyzed in human ADSCs and SM-MSCs by microarray-based and quantitative PCR approaches. We aimed at the identification of miRNAs involved in the maintenance of these MSCs and regulation of osteogenic differentiation of ADSCs and SM-MSCs.

2016-02-01 | GSE72429 | GEO

Comparative analysis of proteomes and secretomes of human mesenchymal stem cells isolated from six sources during osteogenic differentiation

Project description:Ability to perform osteogenic differentiation is one of the minimal criteria of mesenchymal stem cells (MSCs). Still, it is generally unknown whether osteogenic differentiation is universal cell fate or various phenotypically similar cell states. Besides this, MSCs and their secretomes are actively using for cell/cell-free therapy development, but systemic inter-source variation in MSCs secretomes, proteomes and differentiation mechanisms are still poorly understood. Therefore, here we compared proteomic and secretomic profiles of human mesenchymal cells from six sources: osteoblasts (bone), WJ-MSCs (Warton’s jelly), AD-MSCs (adipose), PDLSCs (tooth: Periodontal Ligament Stem Cells), DPSCs (tooth: Dental Pulp Stem Cells) and GFs (tooth: Gingival Fibroblasts). For experiments we used cells in early passages (3-5) isolated from 3-6 individuals. All cells were compared in standard cultivation and in the 10th day after induction of osteogenic differentiation.

2023-11-05 | PXD037320 | Pride

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