Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Postnatal day 1.5 small intestine transcriptome analysis in wild type and ASE-/- mice

ABSTRACT: Postnatal day 1.5 small intestine transcriptome analysis in wild type and ASE-/- mice

PROVIDER: PRJNA673910 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12967754.fastq.gz	Fastqsanger.gz
	SRR12967755.fastq.gz	Fastqsanger.gz
	SRR12967756.fastq.gz	Fastqsanger.gz
	SRR12967757.fastq.gz	Fastqsanger.gz
	SRR12967758.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 7

Similar Datasets

Postnatal day 1.5 small intestine transcriptome analysis in wild type and ASE-/- mice

Project description:By comparing the small intestine transcriptomes of 4 wild type and 3 ASE-/- mice, we identified several oxidative balance related genes are exressed differentially between WT and ASE-/- in postnatal day 1.5 small intestine when dietary nutrient uptake became vital to support neonatal physiology. We here discover that the asymmetry enhancer of Pitx2 is critical for proper redox homeostasis.This is in agreement with the previous discovery that Pitx2 is important for cellular oxidative balance and is therefore important in cellular maturation and differentiation.

2021-11-01 | GSE160677 | GEO

Transcription profiling of mouse small intestine at postnatal days 4,7,9,11,24 to investogate postnatal development of the small intestine

Project description:It was the purpose to analyse the changes in gene expression which occur in the mouse small intestine from the pre-weaning to the post-weaning stage. The gene expression was accordingly followed from postnatal day 4 to postnatal day 32. Experiment Overall Design: 6 time-points were defined corresponding to postnatal day 4, 7, 9, 11, 24 and 32. Ileal samples were taken from individual mice at each time-point. All layers of the small intestine were included in the sample. Three samples from individual mice were analysed by hybridization to Affymetrix GeneChips.

2008-06-16 | E-GEOD-8065 | biostudies-arrayexpress

Gene expression during early postnatal development of the small intestine

2007-06-12 | GSE8065 | GEO

Single-cell RNA sequencing of developing mouse small intestine

Project description:The mammalian intestine is a self-renewing organ that processes ingested food, absorbing nutrients from a sea of biochemical, mechanical, and pathogenic insults. To understand the developmental specification of diverse cell types in the small intestine, we performed time-resolved single-cell transcriptomics across five stages intestinal development: embryonic days (E) 12.5, 14.5, 16.5, and 18.5, and postnatal day (P) 1.5. By dissociating cells from whole organ preparations, we captured the full range of cellular diversity across all intestinal cell lineages. This allowed us to reconstruct the mesenchymal differentiation trajectory and identify the specific genetic programs that give rise to the diverse musculature of the gut wall and villus stroma.

2023-01-12 | GSE222122 | GEO

RNA-seq of Wild-type and Math5-/- mouse dLGN (dorsolateral geniculate nucleus) at postnatal day 3, postnatal day 7, postnatal day 14 and postnatal day 23

Project description:RNA-seq of Wild-type and Math5-/- mouse dLGN (dorsolateral geniculate nucleus) at postnatal day 3, postnatal day 7, postnatal day 14 and postnatal day 23

| PRJNA516465 | ENA

IL-22 promotes formation of MUC17 glycocalyx barrier in postnatal small intestine during weaning

Project description:The intestine is under constant exposure to chemicals, antigens and microorganisms from the external environment. Apical aspects of absorptive epithelial cells form a brush border membrane (BBM), shaped by packed microvilli coated with a dense glycocalyx. We present evidence showing that the glycocalyx forms an epithelial barrier that prevents exogenous molecules and live bacteria from gaining access to BBM. We used a multi-omics approach to investigate function and regulation of membrane mucins exposed on the BBM during postnatal development of the mouse small intestine. Muc17 was identified as a major membrane mucin in the glycocalyx that was specifically upregulated by IL-22 as part of an epithelial defense repertoire during weaning. High levels of IL-22 at time of weaning reprogrammed neonatal postmitotic progenitor enterocytes to differentiate into Muc17-expressing enterocytes, as found in adult intestine during homeostasis. Our findings propose a role for Muc17 in epithelial barrier function in small intestine.

2021-02-16 | GSE164552 | GEO

Whole brain expression data from postnatal day 7-aged mice exposed to ethanol at postnatal day 7

Project description:The developing brain is particularly sensitive to ethanol during the brain growth spurt or synaptogenesis (third human trimester equivalent). This has been shown to lead to abnormal brain development and behavioural changes in the adult mouse that are relevant to those seen in humans with fetal alcohol spectrum disorders (FASD). We evaluated the acute (4h post-treatment) gene expression changes that occur in the brain due to ethanol exposure during synaptogenesis (postnatal day 7). We used microarray analyses to evaluate the changes in brain gene expression at postnatal day 7 that occur due to ethanol treatment at postnatal day 7 (synaptogenesis).

2014-07-18 | GSE59512 | GEO

Rat feces at postnatal day 7

Project description:Rat feces at postnatal day 7 Raw sequence reads

| PRJNA795716 | ENA

WGBS from intestine (ENCSR353IFP)

Project description:Whole genome bisulfite-seq on postnatal 0 day mouse intestine For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2016-06-22 | GSE82632 | GEO

microRNA-seq from intestine (ENCSR832DUZ)

Project description:miRNA-seq on postnatal 0 day mouse intestine For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf

2016-06-22 | GSE82964 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data