Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional effects of KLF15 deletion in soleus muscle

ABSTRACT: Transcriptional effects of KLF15 deletion in soleus muscle

PROVIDER: PRJNA674632 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR12981616_1.fastq.gz	Fastqsanger.gz
	SRR12981616_2.fastq.gz	Fastqsanger.gz
	SRR12981617_1.fastq.gz	Fastqsanger.gz
	SRR12981617_2.fastq.gz	Fastqsanger.gz
	SRR12981618_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 16

Similar Datasets

Transcriptional effects of KLF15 deletion in soleus muscle

Project description:We report bulk RNA-sequencing of soleus muscle harvested from MyoCre and skeletal muscle specific KLF15 (K15-SKO) mice

2021-02-17 | GSE160848 | GEO

Transcriptional effects of KLF15 deletion in quadriceps muscle

Project description:Transcriptional effects of KLF15 deletion in quadriceps muscle

| PRJNA674758 | ENA

Transcriptional effects of KLF15 deletion in quadriceps muscle

Project description:We report bulk RNA-sequencing of quadriceps muscle harvested from MyoCre and skeletal muscle specific KLF15 (K15-SKO) mice

2021-02-17 | GSE160877 | GEO

Transcriptional effects of forced KLF15 over-expression in mouse muscle.

Project description:Excessive or sustained glucocorticoid (GC) exposure causes muscle wasting. Paradoxically, moderate or transient GC exposure elicits ergogenic effects, evidenced by their widespread use as doping agents by endurance athletes and poorly understood efficacy in Duchenne muscular dystrophy (DMD), a genetic muscle wasting disease. While mechanisms underlying GC-mediated muscle wasting are well defined, the molecular basis for the latter remains unknown. In this arm of our studies, we compare expression profiles in quadriceps tissue from KLF15 transgenic (MTg) and non-Tg mice.

2015-12-01 | GSE74623 | GEO

Genome-wide transcriptional targets of KLF15 in human airway smooth muscle

Project description:We previously demonstrated that the transcription factor, KLF15, is a glucocorticoid-regulated gene that represses primary human airway smooth muscle (ASM) proliferation. Here, we show that KLF15 also represses ASM hypertrophy. To uncover the mechanistic basis for these effects, we integrated transcriptome data from KLF15 over-expression with genome-wide analysis of RNA Polymerase II (RNAPII) and glucocorticoid receptor (GR) occupancy (i.e. ChIP-seq). This led us to identify PLCD1 as both a KLF15-regulated gene and a repressor of ASM hypertrophy.

2017-05-01 | GSE95397 | GEO

Soleus muscle

Project description:Expression analysis in order to elucidatethe role of hormone-sensitive lipase in soleus muscle. Keywords: other

2005-09-16 | GSE1772 | GEO

Gene Expression Changes in Soleus Muscle in Mice after Pericytes-Deletion

Project description:Gene Expression Changes in Soleus Muscle in Mice after Pericytes-Deletion

| PRJNA954284 | ENA

KLF15- and glucocorticoid-dependent transcriptional responses in mouse muscle.

Project description:Excessive or sustained glucocorticoid (GC) exposure causes muscle wasting. Paradoxically, moderate or transient GC exposure elicits ergogenic effects, evidenced by their widespread use as doping agents by endurance athletes and poorly understood efficacy in Duchenne muscular dystrophy (DMD), a genetic muscle wasting disease. While mechanisms underlying GC-mediated muscle wasting are well defined, the molecular basis for the latter remains unknown. In this arm of our studies, Wild-type (WT) and Klf15-/- (KO) mice were given the potent GC receptor agonist dexamethasone (dex) and quadriceps tissue was subjected to transcript expression profiling by cDNA microarrays.

2015-12-01 | GSE74624 | GEO

Skeletal muscle of Eif6 heterozygous mice - soleus

Project description:Soleus muscle from Eif6 heterozygous mice and wild-type mice profiled using Agilent gene expression arrays

2018-07-07 | GSE116714 | GEO

Gene expression profile in mouse skeletal muscle after Mettl21c deletion

Project description:Analysis of soleus (SOL) muscle isolated from wildtype (WT) and Mettl21cLacZ/LacZ mice (KO). Results provide unbiased gene expression profile of SOL muscle after Mettl21c deletion.

2022-10-01 | GSE122053 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data