Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Contrasting fungal responses to wildfire across different ecosystem types

PROVIDER: PRJNA679734 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13121000_1.fastq.gz	Fastqsanger.gz
	SRR13121000_2.fastq.gz	Fastqsanger.gz
	SRR13121001_1.fastq.gz	Fastqsanger.gz
	SRR13121001_2.fastq.gz	Fastqsanger.gz
	SRR13121002_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 172

Similar Datasets

Fungal fire

Project description:Contrasting soil fungal communities in Mediterranean pine forests subjected to different wildfire frequencies

| PRJEB5987 | ENA

Functional Variant Discovery Identifies SPRY2 as a Genetic Mechanism Linking Wood Smoke with Asthma

Project description:Climate change is impacting human health through a historic rise in wildfire smoke across the United States and the world. Whereas the deleterious effects of wildfire smoke and associated air pollution on asthma outcomes are well-established epidemiologically, genetic risks and molecular mechanisms of how wildfire smoke affects asthma are unknown. This knowledge gap hinders the identification of high-risk individuals and the creation of targeted therapies or recommendations to protect these individuals. Here, we employ a genetic approach to identify common variant (minor allele frequency > 0.05) exposure-conditional genetic risk variants that localize with genomic responses to wood smoke particles (WSP), a model of wildfire smoke exposure, and associate with asthma in the Genetic Epidemiology Research on Aging (GERA) cohort. Our novel approach used nascent transcriptional signatures derived from WSP-exposed Beas-2B airway epithelial cells to reduce the genome sequence for discovery and allow a permutation-based statistical approach to identify 52 candidate SNPs. We applied biologic and bioinformatic filters to prioritize variants for direct testing of allele-dependent transcriptional regulatory function in plasmid reporters. The rs3861144 variant identified by this approach controls WSP responses of airway epithelial cells to SPRY2, which we showed is involved in mechanical injury repair in cell culture. Our results demonstrate that wildfire particulates contribute to asthma risk at the molecular level, and we have identified mechanistic targets and genetic variant candidates to apply for clinical risk prediction and development of targeted therapies for high-risk individuals.

2024-12-02 | GSE283113 | GEO

rhizosphere soil

Project description:Contrasting responses of multi-spatial soil fungal communities

| PRJNA774433 | ENA

rhizosphere soil

Project description:Contrasting responses of multi-spatial soil fungal communities

| PRJNA853464 | ENA

Project description:Soil fungal diversity under different vegetation types.

| PRJNA1191419 | ENA

Homo sapiens

Project description:HCMV virus produced in different cell types induces different transcriptional responses

| PRJNA103407 | ENA

Across-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis

Project description:Cancer vaccines, reassembled from whole tumor tissue components, were applied to demonstrate the across-cancer immune responses, thanks to inducing pan-clones T cells immune responses. It is demonstrated that across-cancer immune responses among different types of cancers exist and can be induced by nanovaccines or microvaccines, which thus can prevent different types of cancers and cancer metastasis. In addition, ths study revealed that such across-cancer immune responses among different types of cancers is induced by the fact that many neoantigens are shared by different types of cancer cells.

2022-10-24 | PXD037688 |

Arabidopsis root Fe deficiency transcriptome

Project description:Fe deficiency stimulates a coordinated response involving reduction, transport and redistribution of Fe in the roots. The expression of genes regulated by Fe deficiency in the two contrasting Arabidopsis thaliana ecotypes, Tsu-1 and Kas-1, shows that different ecotypes can respond in diverse ways, with different Fe regulated overrepresented categories. We use microarrays to analyze the Fe deficiency responses of contrasting Arabidopsis thaliana ecotypes (Tsu-1 and Kas-1).

2011-10-06 | GSE29086 | GEO

Project description:Contrasting responses of different mixotrophic protists to light and nutrient manipulation

| PRJNA1002229 | ENA

Project description:Responses of soil fungal communities to changes in different land use types in the Yellow River wetland

| PRJNA1164478 | ENA