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Moraxella catarrhalis

ABSTRACT: Moraxella catarrhalis Genome sequencing

PROVIDER: PRJNA688249 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
		Other
	JAEOBF01.dat.gz	Other
	JAEOBF01.fasta.gz	Fasta.gz
	JAEOBF01.master.dat	Other
	JAEOBG01.dat.gz	Other

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Moraxella catarrhalis

Project description:Moraxella catarrhalis Genome sequencing

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Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

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Analysis of the Zur Regulon of Moraxella catarrhalis

Project description:This series of microarrays explores the genes regulated by the Zur gene of Moraxella catarrhalis.

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Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression Moraxella catarrhalis strain BBH18 during adherence to human phanryngeal epithelial Detroit 562 cells

Project description:During the course of infection, respiratory pathogens like Moraxella catarrhalis needs to adhere to epithelial cells of different host niches such as the nasopharynx and lungs. Consequently, efficient adhesion to epithelial cells is considered an important virulence trait of M. catarrhalis. We examined the interaction between human pharyngeal epithelial Detroit 562 cells and M. catarrhalis BBH18 during adherence using a combination of Tn-seq, a genome-wide negative selection screenings technology, and expression profiling of both host and pathogen. The results described in this study are further discussed in Stefan P.W. de Vries, Marc J. Eleveld, Peter W.M. Hermans, Hester J. Bootsma: Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells, submitted.

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Characterization of the molecular interplay between Moraxella catarrhalis and human respiratory tract epithelial cells: Expression response of human phanryngeal epithelial Detroit 562 cells to adherent Moraxella catarrhalis strain BBH18

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Moraxella catarrhalis

Project description:Moraxella catarrhalis Genome sequencing and assembly

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Gene Expression Profile of Moraxella catarrhalis Grown in Pooled Human Sputum

Project description:Comparison of the gene expression profile of Moraxella catarrhalis grown in the presence of 20% pooled human sputum in chemically-defined medium relative to Moraxella catarrhalis grown in chemically-defined medium alone. Moraxella catarrhalis ATCC43617 was grown to mid-logarithmic phase either in the presence of 20% pooled human sputum in chemically-defined medium or in chemically-defined medium alone. Total RNA was extracted from bacterial cells exposed to each of these conditions and cDNA was generated for CyDye labelling. 3 biologic replicates were generated and each replicate underwent a dye swap (total of 6 experimental data collections). The gene expression profile reported is that of Moraxella catarrhalis grown in the presence of pooled human sputum in a chemically-defined medium relative to Moraxella catarrhalis grown only in the presence of the chemically-defined medium.

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Cytosolic immunity against Moraxella catarrhalis requires innate immune signalling pillars converging on inflammasome activation

Project description:RNA-sequencing of uninfected and Moraxella catarrhalis-infected bone marrow-derived macrophages (BMDMs) isolated from Ifnar1 knockout and wild-type mice.

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