Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Galapagos phytoplankton 18S rDNA amplicon

PROVIDER: PRJNA689599 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13377400_1.fastq.gz	Fastqsanger.gz
	SRR13377400_2.fastq.gz	Fastqsanger.gz
	SRR13377401_1.fastq.gz	Fastqsanger.gz
	SRR13377401_2.fastq.gz	Fastqsanger.gz
	SRR13377402_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 101

Similar Datasets

Project description:phytoplankton community 18S rDNA

| PRJNA1013721 | ENA

Galapagos Phytoplankton

Project description:Galapagos Phytoplankton Targeted loci environmental

| PRJNA1105929 | ENA

aquatic metagenome

Project description:Tolo Harbour 18S rDNA amplicon Targeted Locus (Loci)

| PRJNA219227 | ENA

NEREA 18S rDNA

Project description:18S rDNA amplicon sequencing of NEREA size-fractionated samples

| PRJEB74658 | ENA

Project description:18S V4 rDNA amplificons of phytoplankton from central Qinghai-Tibet Plateau lakes

| PRJNA865087 | ENA

LDS-18S-amplicons

Project description:Microbes in drinking water and biofilms (18S rDNA amplicon study)

| PRJEB34250 | ENA

Project description:18S rDNA sequencing

| PRJNA1154839 | ENA

Project description:18s rDNA sequence

| PRJNA734432 | ENA

Project description:18S rDNA sequencing

| PRJNA795277 | ENA

Assessing effect of CEBPA degradation on rRNA transcription machinery

Project description:We report the effect of degradation of CEBPA (a critical myeloid lineage transcription factor) on the occupancy of core rRNA transcription machinery on rDNA in mouse GMP cells. We generated a CEBPA-Degron line by tagging endogenous alleles of the Cebpa gene with the FKBPV degron domain, and degraded CEBPA-FKBPV-FLAG fusion protein using dTAGV-1 ligand. We used anti-FLAG pulldown to demonstrate binding of CEBPA protein to rDNA at a conserved motif within the 18S transcribed region. On degradation of CEBPA, we found that RPA194 (component of Pol I) and RRN3 occupancy on rDNA were reduced, while the occupancy of upstream factors TAF1B (component of SL-1) and UBTF were unchanged. In parallel, we also found that CEBPA degradation reduced nascent rRNA transcription, cellular ribosome abundance, and cell growth. Our work indicates that the cell-type-specific transcription factor CEBPA recruits the Pol I-RRN3 complex to ribosomal DNA to promote rRNA transcription.

2022-01-15 | GSE193569 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data