Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: Diversification, disparification, and hybridization in the desert shrubs Encelia

PROVIDER: PRJNA691962 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13433200_1.fastq.gz	Fastqsanger.gz
	SRR13433200_2.fastq.gz	Fastqsanger.gz
	SRR13433201_1.fastq.gz	Fastqsanger.gz
	SRR13433201_2.fastq.gz	Fastqsanger.gz
	SRR13433202_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 144

Similar Datasets

Project description:Natural selection maintains species despite frequent hybridization in the desert shrub Encelia

| PRJNA675657 | ENA

Spialia spp.

Project description:Hybridization fuelled diversification in Spialia butterflies

| PRJNA771264 | ENA

Quaternary diversification of a columnar cactus in the driest place on earth

Project description:Diversification of Eulychnia in the Atacama Desert

| PRJEB39114 | ENA

Encelia farinosa

Project description:Encelia farinosa Assembly

| PRJNA812527 | ENA

Project description:Hybridization fueled diversification: increased risk or persistence under global changes?

| PRJNA901621 | ENA

Project description:Population Structure and Natural Selection across a Flower Color Polymorphism in the Desert Plant Encelia farinosa

| PRJNA1109372 | ENA

PHY-ROSE

Project description:Phylogenomics of the genus Rosa - polyploidy and hybridization as diversification forces

| PRJEB38929 | ENA

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival [ATAC-seq]

Project description:Gene deserts spanning more than 500kb of non-protein coding genomic sequence are considered evolutionarily ancient and stable and are enriched in the vicinity of developmental regulator genes (Ovcharenko 2005). These extensive genomic regions typically harbor numerous conserved elements with predicted gene regulatory potential pointing to critical tissue-specific functions during development. Nevertheless, the biological necessity and underlying funtional enhancer landscapes of most gene deserts near developmental transcription factors (TFs) remain unknown, and it is unclear how precise pleiotropic expression patterns emerge from gene desert sequence. Here, we investigated the cis-regulatory architecture and function of a gene desert flanking the mouse Shox2 transcriptional regulator which itself is essential for embryonic limb, craniofacial, and cardiac pacemaker development. By combining epigenomic enhancer prediction, transgenic reporter validation and region-specific chromatin capture (C-HiC), we define the embryonic in vivo enhancer landscape and chromatin topology of the Shox2 gene desert. Targeted and context-specific genomic deletions uncover the gene desert not only as a regulator of embryonic survival through enhancer-mediated control of cardiac Shox2 expression, but also link distinct subsets of tissue-specific gene desert enhancers to the regulation of craniofacial patterning and proximal limb development. Our results hence identify the Shox2 gene desert as a fundamental genomic unit indispensable for pleiotropic patterning, robust organ morphogenesis and embryonic development progression by serving as a dynamic hub for tissue-specific developmental enhancers.

2024-06-01 | GSE232882 | GEO

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival [ChIP-seq]

2024-06-01 | GSE232883 | GEO

Encelia californica

Project description:Encelia californica Genome sequencing and assembly

| PRJNA832767 | ENA