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ABSTRACT: Fecal microbiota in cats infected with Tritrichomonas foetus

PROVIDER: PRJNA692463 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR13446050_1.fastq.gz	Fastqsanger.gz
	SRR13446050_2.fastq.gz	Fastqsanger.gz
	SRR13446051_1.fastq.gz	Fastqsanger.gz
	SRR13446051_2.fastq.gz	Fastqsanger.gz
	SRR13446052_1.fastq.gz	Fastqsanger.gz

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Project description:Fecal microbiota in cats with naturally-occurring Tritrichomonas foetus infection

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The Effects of Bacillus licheniformis-fermented Products on Chronic Feline Diarrhea and Intestinal Microbiota

Project description:Bacillus licheniformis-fermented products (BLFP) are probiotics with antibacterial, antiviral, and anti-inflammatory properties that can improve growth performance. This study aimed to, firstly, compare the fecal microbiota of cats with chronic diarrhea (n = 8) with that of healthy cats (n = 4) from the same household using next-generation sequencing and, secondly, evaluate the effectiveness of oral administration of BLFP in relieving clinical signs and altering the intestinal microbiota in diarrheal cats. Six out of eight cats with diarrhea showed clinical improvement after BLFP administration for 7 days, and in two cats the stool condition was normal. A higher Firmicutes/Bacteroidetes ratio was noted in the feces of diarrheal cats without clinical improvement as compared with those in the healthy control group and in the diarrheal cats with clinical improvement after receiving BLFP. The phylum Bacteroidetes and class Bacteroidia decreased significantly in diarrheal cats regardless of BLFP administration. Blautia spp., Ruminococcus torques, and Ruminococcus gnavus, which belong to the Clostridium cluster XIVa and have been reported as beneficial to intestinal health, increased significantly in feces after BLFP treatment. Furthermore, a significant decrease in Clostridium perfringens was noted in diarrheal cats after BLFP administration. Overall, BLFP could be a potential probiotic to relieve gastrointestinal symptoms and improve fecal microbiota in cats with chronic diarrhea.

2022-08-24 | GSE203254 | GEO

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