Project description:single-cell Gene expression signatures in gastric tissues of sstr2 knockout and wild type mice using Chromium’s 10x single-cell RNA-seq platform

2023-01-17 | GSE166113 | GEO

Single-cell RNA sequencing of sstr2 knockout mice

Project description:Single-cell RNA sequencing of sstr2 knockout mice

| PRJNA699280 | ENA

RNA sequencing of SSTR2 overexpression or knockout in gastric cancer cell lines

Project description:Gene expression signatures in SSTR2 overexpression or knockout and control gastric cancer cell lines using RNA sequencing

2023-01-04 | GSE193993 | GEO

Whole genome bisulfite sequencing of Ing1/Gadd45a double knockout and wildtype mouse embryonic fibroblasts

Project description:ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA repair. We previously found that ING1b is essential to target GADD45a-mediated active DNA-demethylation via TET1 to specific loci. In order to study the physiological impact of ING1-GADD45a on DNA methylation in base-resolution genome-wide, we compared the methylation levels of wildtype mouse embryonic fibroblasts (MEFs) with Ing1/Gadd45a double-knockout MEFs via whole genome bisulfite sequencing.

2018-06-11 | GSE99601 | GEO

NPC268 whole-genome bisulfite sequencing (WGBS)

Project description:NPC268 whole-genome bisulfite sequencing (WGBS)

| PRJNA976248 | ENA

Whole-genome bisulfite sequencing analysis of Pten's function in regulating cardiomyocyte differentiation

Project description:We report the function of Pten in regulating the cardiomyocyte differentiation, and then we performed whole-genome bisulfite sequencing for the wild-type and Pten knockout embryoid bodies and cardiomyocytes to analyse the methylomes. The results showed a significant difference between wild-type and Pten knockout groups in methylomes, and we performed a series of experiments to study the function of Pten in cardiogenesis.

2021-07-09 | GSE160236 | GEO

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