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Expression data of the livers of male C57Bl6/N mice after i.p. injection of lipopolysaccharide (LPS)

ABSTRACT: Expression data of the livers of male C57Bl6/N mice after i.p. injection of lipopolysaccharide (LPS)

PROVIDER: PRJNA701046 | ENA |

REPOSITORIES: ENA

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Expression data of the livers of male C57Bl6/N mice after i.p. injection of lipopolysaccharide (LPS)

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Expression data of the livers of male C57Bl6/N mice after i.p. injection of CCl4

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Expression data of the livers of male C57Bl6/N mice after i.p. injection of paracetamol (APAP)

Project description:Expression data of the livers of male C57Bl6/N mice after i.p. injection of paracetamol (APAP)

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Expression data of the livers of male C57Bl6/N mice after i.p. injection of paracetamol (APAP)

Project description:Male C57BL6/N mice were obtained from Janvier Labs (France). Mice were starved overnight before APAP administration and were fed ad libitum afterward. A single dose of 300 mg APAP/kg b.w. was intraperitoneally injected in warm phosphate-buffered saline (PBS; Table 3). The used APAP was obtained from Sigma-Aldrich (A7085-500G, Germany). The mice were sacrificed at 1, 6, and 12 hours, and on days 1, 2, 4, 6, and 8 after APAP administration. Expression data of the livers of male C57Bl6/N mice after intoxication with paracetamol (APAP)

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Expression data of the livers of male C57Bl6/N mice after i.p. injection of CCl4

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Macrophage response to lipopolysaccharide

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Transcriptional profiling of mouse glomerulus in lipopolysaccharide-induced proteinuria model

Project description:The pathogenic mechanisms of common kidney glomerular diseases, including the vast majority of cases of proteinuria, remain unknown. To gain insight into the pathogenesis of proteinuria development, we characterized the glomerular gene expression changes that accompany early stages of proteinuria induced by lipopolysaccharide (LPS) in mice. Nine-week-old female C57Bl6 mice were allocated to LPS-treated group (n=6) or PBS control group (n=4), and subsequently treated either by a single intraperitoneal injection LPS or control buffer.

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Skeletal muscle of adrenalectomized mice with and without a glucocorticoid injection 3 or 24 h previously (MG-U74Av2)

Project description:Forty male C57BL6 mice 12-15 weeks old fed chow ad libitum. 30 mice underwent adrenalectomy (Adx) and 10 others a sham-Adx. Three or 24h before tissue sampling, groups of 10 mice received an I.P. injection of cortisol (0.1 mg per mice), while the remaining Adx and intact mice received an I.P. injection of the vehicle (ethanol) 24 h prior to the sacrifice. All mice were killed within a period of a few hours. Gastrocnemius muscle were dissected and pooled together for each one of the four groups. Total RNA was isolated by Trizol. Samples were processed following the labeling protocol from Affymetrix. In the MG-U74A2, each of the 12488 murine transcripts are represented by 16 probe pairs of 25mer. Images were scanned using a GeneChip scanner 3000 with autoloader, and analyzed with the MAS 5.0 software (Affymetrix). The ratio of fluorescence intensities for the 5' end and the 3' end of beta-actin and glyceraldehyde 3-phosphate dehydrogenase was less than 2. This microarray analysis was performed once. Keywords = Skeletal muscle Keywords = gastrocnemius Keywords = adrenalectomy Keywords = glucocorticoids Keywords: other

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LPS Blood Time course

Project description:cDNA microarray study of gene expression changes in whole blood from LPS treated rats, 2 and 6 hours after I.P. injection of 5 mg/kg Keywords: time-course

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