Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single-cell RNAseq analysis of mesenchymal cells in the periodontal space of the murine molar

ABSTRACT: Single-cell RNAseq analysis of mesenchymal cells in the periodontal space of the murine molar

PROVIDER: PRJNA707439 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13884915.fastq.gz	Fastqsanger.gz

Items per page:

1 - 1 of 1

Similar Datasets

Single-cell RNAseq analysis of mesenchymal cells in the periodontal space of the murine molar

Project description:A single cell transcriptional profile of mesenchymal cells in the periodontal space of the murine molar marked by 2.3kb Col1a1-GFP or PTHrP-creER-lineage marked cells at postnatal day 25 (P25)

2021-03-09 | GSE168450 | GEO

Single-cell RNAseq analysis of CXCL12+ mesenchymal cells of the murine molar

Project description:A single cell transcriptional profile of mesenchymal cells in the murine molar marked by CXCL12-GFP, Col1a1-GFP or CXCL12-creER+ cells at postnatal day 6 or 25 (P6 or P25)

2023-12-01 | GSE248300 | GEO

Single-cell RNAseq analysis of CXCL12+ mesenchymal cells of the murine molar

Project description:Single-cell RNAseq analysis of CXCL12+ mesenchymal cells of the murine molar

| PRJNA1043187 | ENA

Single-cell RNAseq analysis of Gli1-GFP+ tooth roor progenitor cells and PTHrP+ dental follicle cells of the murine molar

Project description:A single cell transcriptional profile of both epithelial and mesenchymal cells in the tooth bud of the murine molar marked by Gli1-GFP+ tooth root progenitor cells or PTHrP+ dental follicle cells at postnatal day 6 (P6)

2023-07-19 | GSE237439 | GEO

Differentially expressed long noncoding RNA expression between periodontal ligament stem cells from healthy periodontal tissue and periodontal ligament stem cells from inflammatory periodontal tissue.

Project description:Periodontitis can impair the osteogenic differentiation of human periodontal mesenchymal stem cells, but the underlying molecular mechanisms are still poorly understood. Long noncoding RNAs (lncRNAs) have been demonstrated to play significant roles under both physiologic and pathological conditions. We performed comprehensive lncRNAs profiling by lncRNA microarray to identify differentially expressed long noncoding RNA expression between Periodontal ligament stem cells from healthy Periodontal tissue and periodontal ligament stem cells from inflammatory periodontal tissue. Our analysis identified 233 lncRNAs and 423 mRNAs that were differently expressed (fold change >2.0, p-value < 0.05) between the two groups of cells. The GO analysis revealed that the significantly down-regulated biological processes included multicellular organismal process, developmental process and multicellular organismal development and the significantly up-regulated biological processes included cellular process, biological regulation and response to stimulus in periodontal ligament stem cells from inflammatory periodontal tissue. The Pathway analysis revealed that the differentially expressed mRNAs may involved in Focal adhesion, ECM-receptor interaction, Bacterial invasion of epithelial cells, Long-term depression, Circadian entrainment and HIF-1 signaling pathway. Two-condition experiment, periodontal ligament stem cells from healthy periodontal tissue (hPDLSCs) vs. periodontal ligament stem cells from inflammatory periodontal tissue (pPDLSCs), Biological replicates: 3 control replicates (hPDLSCs), 3 testing replicates (pPDLSCs).

2016-02-19 | E-GEOD-78074 | biostudies-arrayexpress

Murine Tooth Embryoic Molar Germ; E11, 12, 16, 18

Project description:Transcriptional profiling of mouse E14 tooth molar germ comparing E11, 12, 16, 18 tooth molar germ. Goal was to identify unknown genes involved in tooth development,

2020-11-20 | GSE161851 | GEO

2016-02-19 | GSE78074 | GEO

scRNA-seq analysis of murine periodontal ligament

Project description:Periodontal tissue supports teeth in the alveolar bone socket via fibrous attachment of the periodontal ligament (PDL). The PDL contains many stromal cell types, including osteoblasts, cementoblasts, periodontal fibroblasts, and stem/progenitor cells. However, the characteristics and lineage hierarchy of each cell type remain poorly defined. Here we present a single-cell atlas of PDL, highlighting diverse cell populations in PDL.

2022-09-28 | GSE197828 | GEO

Comparison of long non-coding RNA expression profiles in human periodontal tissue cells

Project description:Human dental follicle cells (hDFCs) are precursor cells of periodontal development. Long non-coding RNAs (lncRNAs) have been revealed to be crucial factors that regulate a variety of biological processes; however, whether lncRNAs serve a role in human periodontal development remains unknown. Therefore, the present study used microarrays to detect the differentially expressed lncRNAs and mRNAs between hDFCs and human periodontal ligament cells (hPDLCs). Human dental follicle and periodontal ligament samples were obtained from four adolescents (2 males and 2 females) between 12 and 16 years old following premolar and immature impacted third molar (roots developed to <2/3 their full size) extraction for orthodontic reasons. To verify the reliability of the microarray data, six differentially expressed lncRNAs and six differentially expressed mRNAs were randomly selected for analysis of their expression levels by RT-qPCR.

2019-08-06 | GSE124352 | GEO

Transcriptome characterization of human gingival mesenchymal and periodontal ligament stem cells in response to Electronic-cigarette

Project description:The change of transcriptome and related biological functions affected by tobacco smoke and Electronic-cigarette (E-cig) to human gingival mesenchymal (GMSC) and periodontal ligament stem cells (PDLSCs) are not fully understood. Here, we collected GMSCs and PDLSCs from systemically healthy patients due to the premolars and extracted for orthodontic reasons, and treated with tobacco smoke (G1, P1), E-cig smoke with original flavor (G2, P2), E-cig smoke with menthol flavor (G3, P3), E-cig liquid with original flavor (G4, P4), and E-cig liquid with menthol flavor (G5, P5) by the optimal conditions of LC50, and conducted RNA-seq to compare with untreated control (G0, P0).

2022-06-17 | E-MTAB-11797 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data