Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptional profiling of WT Tregs and Tregs sorted from K14cre Cdh1F/F Trp53F/F mice bearing 225mm2 mammary tumors from blood, spleen, lungs, TDLNs, tumor and healthy mammary gland [Treg]

ABSTRACT: Transcriptional profiling of WT Tregs and Tregs sorted from K14cre Cdh1F/F Trp53F/F mice bearing 225mm2 mammary tumors from blood, spleen, lungs, TDLNs, tumor and healthy mammary gland [Treg]

PROVIDER: PRJNA714920 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR13979000.fastq.gz	Fastqsanger.gz
	SRR13979001.fastq.gz	Fastqsanger.gz
	SRR13979002.fastq.gz	Fastqsanger.gz
	SRR13979003.fastq.gz	Fastqsanger.gz
	SRR13979004.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 31

Similar Datasets

Transcriptional profiling of WT Tregs and Tregs sorted from K14cre;Cdh1F/F;Trp53F/F mice bearing 225mm2 mammary tumors from blood, spleen, lungs, TDLNs, tumor and healthy mammary gland [Treg]

Project description:We studied the impact of mammary tumorigenesis on Tregs in tumors and distant organs (CD3+CD4+CD25+). Here we generated RNAseq data from sorted Tregs (CD3+CD4+CD25+) from WT and K14cre;Cdh1F/F;Trp53F/F mice bearing 225mm2 mammary tumors from blood, spleen, lungs, TDLNs, tumor and healthy mammary gland

2022-03-01 | GSE169024 | GEO

Characterizing Macrophage Diversity in Metastasis-Bearing Lungs Reveals a Lipid-Associated Macrophage Subset

Project description:Single cell RNA sequencing was performed on CD45+Ly6G-CD64+MerTK+ macrophages isolated from the lungs of mice 5 weeks after transplantation of 4T1-Luc mammary gland tumors. The purpose of this study was to determine the unique macrophage subsets present in the lungs of mice bearing mammary tumor metastases.

2021-08-31 | GSE164302 | GEO

Transcriptional profiling of NK cells sorted from lungs and axillary LNs from Cdh1F/F;Trp53F/F;Foxp3GFP-DTR mice bearing 100mm2 orthotopically transplanted mammary tumors, treated with difteria toxin (DT) or PBS [NK]

Project description:We studied the impact of DT treatment (Treg depletion) on NK cells (CD3-, NKp46+, DX5+) in axillary TDLNs and lungs of tumor bearing Foxp3GFP-DTR mice . Here we generated RNAseq data from sorted NK cells from DT or PBS treated Foxp3GFP-DTR mice bearing 100mm2 mammary tumors from lungs, axillary TDLNs

2022-03-01 | GSE169025 | GEO

Tregs recruited to the omentum and spleen express distinct transcriptomes

Project description:To test whether Tregs that were newly recruited to tumor-bearing omentum had similar properties to those of adipose resident Tregs, we surgically joined tumor-bearing mice with congenic naive mice, sorted partner-derived Tregs from the omenta and spleens of tumor-bearing (CD45.1+) parabionts on day 14 and performed RNAseq analysis

2022-02-25 | GSE181124 | GEO

RNAseq analysis of mouse CD4+ regulatory Tregs in WT and ∆Foxp3 mice isolated from spleen and lungs.

Project description:RNAseq analysis of mouse CD4+ regulatory Tregs in 21-day-old male WT and ∆Foxp3 mice isolated from spleen and lungs.

2021-02-18 | GSE166860 | GEO

mRNA transcriptome sequencing of tumor bearing lungs

Project description:mRNA transcriptome sequencing of tumor bearing lungs

| PRJNA695255 | ENA

Lung gamma delta T cells in tumor-free and mammary tumor-bearing mice

Project description:Gamma delta T cells were sorted from the lungs of 4 female FVB/n mice (labeled wild-type [WT] 1-4) and 4 female mammary tumour-bearing K14-Cre;Brca1F/F;Trp53F/F (KB1P) mice (labeled Tumour 1-4).The sorted cells were loaded onto the Chromium Single Cell 30 Chip Kit v2 (10xGenomics) to generate libraries for scRNAseq, following the manufacturer’s instructions. The sequencing-ready library was cleaned up with SPRIselect beads (Beckman Coulter, High Wycombe, UK). Quality control of the library was performed prior to sequencing (Qubit, Bioanalyzer, qPCR). Illumina sequencing was performed using NovaSeq S1 by Edinburgh Genomics (University of Edinburgh).

2021-07-12 | E-MTAB-10677 | biostudies-arrayexpress

Gene expression in liver and lung of a high-fat diet fed, metastasizing mammary tumor-bearing and obesity-resistant mice

2012-03-05 | GSE36211 | GEO

Gene expression in liver and lung of a high-fat diet fed, metastasizing mammary tumor-bearing and obesity-resistant mice

Project description:We explored early changes in gene expression in the livers and lungs of the HFD-fed, metastasizing mammary tumor-bearing and obesity-resistant mice mice. These alterations may have led to favorable conditions for both the formation of pro-inflammatory and pro-mitotic microenvironments in the target organs that promote immune cell infiltration and differentiation, as well as infiltration and proliferation of metastatic tumor cells. Total RNA was isolated from hepatic and pulmonary tissues of high fat diet fed-4T1 cell-injected mice or high fat diet fed-sham mice. Gene expressions were compared to control diet fed-same conditional mice.

2012-03-05 | E-GEOD-36211 | biostudies-arrayexpress

Expression data for cCD1 cell-sorted from the lungs of healthy or KP tumor-bearing mice

Project description:The goal of this study was to identify mechanism of suppression of cDC1 in a model of genetically driven lung adenocarcinoma (KP). As part of the study we analyzed the transcriptional differences between cDC1 cell-sorted from healthy lung and those cell-sorted from KP bearing lungs.

2021-03-06 | GSE119574 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data