Ontology highlight
ABSTRACT:
PROVIDER: PRJNA719437 | ENA |
REPOSITORIES: ENA
Dataset's files
| Action | DRS | |||
|---|---|---|---|---|
| SRR14138500_1.fastq.gz | Fastqsanger.gz | |||
| SRR14138500_2.fastq.gz | Fastqsanger.gz | |||
| SRR14138501_1.fastq.gz | Fastqsanger.gz | |||
| SRR14138501_2.fastq.gz | Fastqsanger.gz | |||
| SRR14138502_1.fastq.gz | Fastqsanger.gz |
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Project description:Fertility depends on the coordination of complex interactions between male and female reproductive proteins inside the female reproductive tract (FRT). These interactions mediate a suite of changes in female behavior, morphology, and physiology after mating, yet little is known about how the molecular environment of the FRT may differ among species and coordinate species-specific female post-mating responses. We used semi-quantitative proteomics to compare the FRT protein composition between virgin and mated females in Drosophila melanogaster. These results are compared to those from quantitative TMT proteomic analyses of the mating-induced changes in D. simulans and D. mauritiana, and after conspecific and heterospecific inseminations. Our study highlights the value of using quantitative proteomics approaches to study the molecular composition of the FRT environment, and how its divergence may inform mechanistic studies of post-mating pre-zygotic reproductive isolation between species.
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