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Whole transcriptome map of osteoarthritic meniscus with or without interleukin-1β stimulation

ABSTRACT: whole transcriptome map of osteoarthritic meniscus with or without interleukin-1β stimulation

PROVIDER: PRJNA720416 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14166833_1.fastq.gz	Fastqsanger.gz
	SRR14166833_2.fastq.gz	Fastqsanger.gz
	SRR14166834_1.fastq.gz	Fastqsanger.gz
	SRR14166834_2.fastq.gz	Fastqsanger.gz
	SRR14166835_1.fastq.gz	Fastqsanger.gz

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whole transcriptome map of osteoarthritic meniscus with or without interleukin-1β stimulation

Project description:We report the application of whole-transcriptome high throughput sequence on osteoarthritic degenerative meniscus with or without interleukin-1β stimulation. A total of 375 mRNAs, 15 miRNAs, 56 lncRNAs, and 90 circRNAs were significantly altered in the degenerative meniscus treated with IL-1β. qRT-PCR further revealed consistent expression pattern. More importantly, highly specific ceRNA networks regulated by lncRNA LOC107986251-miR-212-5p-SESN3 and hsa_circ_0018069-miR-147b-3p-TJP2 were identified during interleukin-induced meniscus degeneration.

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