Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Colon cancer cells after escape of late apoptosis

ABSTRACT: Colon cancer cells after escape of late apoptosis

PROVIDER: PRJNA720553 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14152300.fastq.gz	Fastqsanger.gz
	SRR14152301.fastq.gz	Fastqsanger.gz
	SRR14152302.fastq.gz	Fastqsanger.gz
	SRR14152303.fastq.gz	Fastqsanger.gz
	SRR14152304.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Colon cancer cells after escape of late apoptosis [exp_1]

Project description:Colon cancer cells after escape of late apoptosis [exp_1]

| PRJNA720012 | ENA

Colon cancer cells after escape of late apoptosis [exp_2]

Project description:Colon cancer cells after escape of late apoptosis [exp_2]

| PRJNA720091 | ENA

Colon cancer cells after escape of late apoptosis [exp_1]

Project description:In order to explore the potential role of escape of late apoptosis in metastasis, we induced apoptosis and subsequently inhibited the death process in a primary culture of colon cancer cells. Here we wanted to explore the transcriptome of such "undead" cells 7 days after apoptosis induction.

2022-03-08 | GSE171543 | GEO

Colon cancer cells after escape of late apoptosis [exp_2]

Project description:In order to explore the potential role of escape of late apoptosis in metastasis, we induced apoptosis and subsequently inhibited the death process in a primary culture of colon cancer cells. Here we wanted to explore the transcriptome of cells treated with the conditioned medium of these surviving cells. Thes cells have been treated for 48h with conditionned media previous RNA extraction and RNAseq.

2022-03-08 | GSE171560 | GEO

Colon cancer cells after escape of late apoptosis

Project description:This SuperSeries is composed of the SubSeries listed below.

2022-03-08 | GSE171679 | GEO

Colon cancer

Project description:Colon cancer

| PRJNA761970 | ENA

Colon cancer

Project description:Colon cancer

| PRJNA300948 | ENA

Cerulenin action on colon cancer cell line

Project description:Showing the anti cancer activity of Cerulenin on colon cancer cell lines. The study shows the mechanismm of apoptosis induction as a result of cerulenin treatment to colon cancer cell lines.

2023-02-05 | PXD023569 | Pride

Peroxireduxin-4 is over-expressed in colon cancer and its down-regulation leads to apoptosis

Project description:The objective of this study was to gain insights into the biological basis of colon cancer progression by characterizing gene expression differences between normal colon epithelium, corresponding colorectal primary tumors and metastases. We found a close similarity in gene expression patterns between primary tumors and metastases, indicating a correlation between gene expression and morphological characteristics. PRDX4 was identified as highly expressed both in primary colon tumors and metastases, and selected for further characterization. Our study revealed that Prdx4 (PrxIV, AOE372) shows functional similarities to other Prx family members by negatively effecting apoptosis induction in tumor cells. In addition, our studies link Prdx4 with Hif-1M-NM-1, a key regulatory factor of angiogenesis. Targeting Prdx4 may be an attractive approach in cancer therapy, as its inhibition is expected to lead to induction of apoptosis and blockade of Hif-1M-NM-1-mediated tumor angiogenesis. mRNA expression profiling of normal colon epithelium (5), primary colon tumors (12 with 1 replicate) and either lymph node metastases (9 with 2 replicates) or liver metastases (2) and cell lines (4) from twelve colon cancer patients.

2011-06-01 | E-GEOD-26571 | biostudies-arrayexpress

Peroxireduxin-4 is over-expressed in colon cancer and its down-regulation leads to apoptosis

Project description:The objective of this study was to gain insights into the biological basis of colon cancer progression by characterizing gene expression differences between normal colon epithelium, corresponding colorectal primary tumors and metastases. We found a close similarity in gene expression patterns between primary tumors and metastases, indicating a correlation between gene expression and morphological characteristics. PRDX4 was identified as highly expressed both in primary colon tumors and metastases, and selected for further characterization. Our study revealed that Prdx4 (PrxIV, AOE372) shows functional similarities to other Prx family members by negatively effecting apoptosis induction in tumor cells. In addition, our studies link Prdx4 with Hif-1α, a key regulatory factor of angiogenesis. Targeting Prdx4 may be an attractive approach in cancer therapy, as its inhibition is expected to lead to induction of apoptosis and blockade of Hif-1α-mediated tumor angiogenesis.

2011-06-01 | GSE26571 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data