Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Effect of infection with VSV-G pseudotyped HIV on the DNA damage response in HCT116 cells

ABSTRACT: Effect of infection with VSV-G pseudotyped HIV on the DNA damage response in HCT116 cells

PROVIDER: PRJNA722273 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14244718_1.fastq.gz	Fastqsanger.gz
	SRR14244718_2.fastq.gz	Fastqsanger.gz
	SRR14244719_1.fastq.gz	Fastqsanger.gz
	SRR14244719_2.fastq.gz	Fastqsanger.gz
	SRR14244720_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 28

Similar Datasets

Effect of infection with VSV-G pseudotyped HIV on the DNA damage response in HCT116 cells

Project description:Effect of infection with VSV-G pseudotyped HIV partiles on HCT116 cells at different time points.

2021-04-16 | GSE172164 | GEO

Genome wide RNA-seq of iBMDMs upon VSV infection

Project description:VSV infection affects various gene expression

2018-10-05 | GSE120820 | GEO

Wild-type and GLO2 knockout BMDMs with infection of VSV

Project description:Transcriptome analysis of wild-type and GLO2 knockout BMDM infected with VSV for 12 hours .

2024-07-01 | GSE248885 | GEO

Effects of HIV infection and opioids on gut microbiota

Project description:Opioid use is associated with worse outcome in HIV-infected patients. The exacerbated disease progression by opioids is mainly driven by increased epithelial damage and less regenerative response. The present study investigates how opioids potentiate HIV disease progression by impairing intestinal epithelial self-repair. Abnormal intestinal morphology and reduced epithelial proliferation were observed in HIV-infected humanized mice, which were exposed to opioids. For this study, we had 4 groups of BLT humanized mice- (A) Untreated, (B) Morphine treated, (C) HIV infected and (D) HIV infected + Morphine treated. HIV infection was done for 4 weeks and Morphine treatment was done for 7 days. Morphine treatment was done via subcutaneous implantation of slow-release morphine pellet in individual mouse in the appropriate groups. In other groups, a matching Placebo pellet was implanted.

2020-01-11 | E-MTAB-7883 | biostudies-arrayexpress

Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection

Project description:This phase I trial studies the side effects and best dose of ibrutinib in treating B-cell non-Hodgkin lymphoma that has returned or does not respond to treatment in patients with human immunodeficiency virus (HIV) infection. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. It is not yet known whether it is safe for patients with HIV infection to receive ibrutinib while also taking anti-HIV drugs.

| 2164362 | ecrin-mdr-crc

Cellular proteomic changes in the immediate early phase of HIV-1 and 2 transduction

Project description:Human immunodeficiency viruses type 1 and 2 (HIV-1 and 2) are known to depend on cellular host machinery for their replication and survival. While most of the studies on cellular proteomic and transcriptomic changes focused on the late-phase of the infection, studies of those changes in the early time-points; especially in the case of HIV-2 infection, are widely lacking. Using 2nd generation HIV-1 and 2 VSV-G pseudotyped lentiviral vectors, we transduced HEK-293T cells, and carried out transcriptomic profiling and proteomic analysis of harvested cells at 2h time point, which is representative of the immediate early-phase events in the infection cycle.

2021-11-03 | PXD024243 | Pride

Transcriptional changes following HIV infection of choroid plexus brain organoids

Project description:We employed iPSC-derived choroid plexus brain organoids to explore the impact of HIV infection on microglia, elucidating alterations in the host gene profile within the central nervous system. We conducted single-cell RNA sequencing to elucidate the changes in microglia upon HIV infection, leading to neural cell damage

2024-04-29 | GSE262349 | GEO

Characterization of the epitranscriptomic landscape of HIV-infected cells IV

Project description:In this study, we used a productive HIV infection model, consisting of the CD4+ SupT1 T cell line infected with a VSV-G pseudotyped HIVeGFP-based vector, to explore the transcriptomic and m6A/m5C epitranscriptomic lansdcape upon HIV infection, and compare it to mock-treated cells at 12h, 24h, and 36h post infection.

2021-06-30 | GSE157192 | GEO

Characterization of the epitranscriptomic landscape of HIV-infected cells III

2021-06-30 | GSE157190 | GEO