Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

ABSTRACT: Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

PROVIDER: PRJNA724727 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Microvessels support engraftment and functionality of human islets and hESC-derived pancreatic progenitors in diabetes models

Project description:Single nuclei sequencing of grafts developed 14 weeks post transplantation of human embryonic stem cell derived pancreatic progenitors alone (PP) or with rat adipose derived microvessels (PPMV) into the subcutaneous pocket of diabetic (STZ-induced) Scid-beige mice.

2021-09-03 | GSE173228 | GEO

Gene expression profiling of the retinal microvessels and the brain microvessels

Project description:Rat retinal microvessels (RMVs) and brain microvessels (BMVs) were mechanically isolated under ice-cold condition. Retinal and brain tissues (RT, BT) from the same animals were collected for comparisons. Total RNA were individually extracted, amplified and processed on Affymetrix rat 2.0 microarray Chips. We sought to obtain the whole gene expression profile of RMVs, RT, BMVs and BT. Differently expressed genes (DEGs) between RMVs and RT, and between RMVs and BMVs, between RT and BT were analyses. Using these DEGs, we comprehensively analyzed gene expression of the microvessels and highlighted their involvement in critical functional structures in RMVs and BMVs, such as junctional complex, transporters and signaling pathways.

2019-10-16 | GSE110675 | GEO

Defining the Phosphodiesterase Superfamily Members in Rat Brain Microvessels

Project description:A filtration method followed by microarray analyses allows PDE components to be identified in brain microvessels, and confirmed that PDE4D and PDE5A are the primary forms expressed in rat brain microvessels. Adult male F344 rats were sacrificed and blocks of the cerebral cortex and infratentorial areas were dissected. Microvessels were isolated using a filtration method, and total RNA was extracted. Two microarrays using four sample RNAs (microvessels from the cerebral cortex vs. microvessels from the infratentorial block) were included in the present study. Microarrays demonstrated that there were 16 PDE transcripts in the PDE superfamily, exhibiting quantifiable density in the microvessels.

2012-02-01 | E-GEOD-35285 | biostudies-arrayexpress

Gene expression profiling of the retinal microvessels and the brain microvessels

Project description:Gene expression profiling of the retinal microvessels and the brain microvessels

| PRJNA434237 | ENA

Stroke-induced transcriptomic alterations in mouse cerebral microvessels

Project description:To investigate the stroke-induced changes in gene expression in cerebral microvessels, we subjected mice to transient middle cerebral artery occlusion (tMCAO) or sham surgeries. 24h hours later, cerebral microvessels were harvested and RNA was isolated. We then performed gene expression profiling analysis using data obtained from RNA-seq of cerebral microvessels isolated from 8 mice (4 shams and 4 tMCAO)

2022-12-24 | GSE221379 | GEO

Defining the Phosphodiesterase Superfamily Members in Rat Brain Microvessels

2012-02-01 | GSE35285 | GEO

Molecular Characterization of Human Breast Tumor Microvessels

Project description:Molecular Characterization of Human Breast Tumor Microvessels Keywords: breast cancer

2007-04-03 | GSE7413 | GEO

Brain microvessels ontogeny-ERI-INSERM28

Project description:Enriched forebrain microvessels from P5, P10 and adult mice. Transcript comparisons identified 5873 genes with FC>2 between ages and 93 pathways. The observations were confronted to proteome study using NanoLS-MS/MS and deposited on proteomeXchange platform under # PXD001718. The 2 techniques converge towards extracellular matrix, cell adhesion and junction pathways, indicating early changes in development. The difference are examined as putative structural basis of very preterm intracerbral hemorrhage, 3 age comparisons of 5 days, 10 days and adult brain microvessels, 2 replicates, Agilent Whole Mouse Genome Oligo 4Ã44K Microarray

2016-01-10 | E-GEOD-67870 | biostudies-arrayexpress

Transcription profiling of human breast tumor microvessels

Project description:Molecular Characterization of Human Breast Tumor Microvessels Experiment Overall Design: LCM & Microarrays

2008-06-15 | E-GEOD-7413 | biostudies-arrayexpress

TMT characterisation: iPSC vs hESC

Project description:Detailed comparison of human pluripotent stem cells, to determine how hESC and iPSC differ in their protein expression profiles. The data was acquired in a TMT 10-plex SPS-MS3. 4 replicates of hESC compared to 4 replicates of HipSci human iPSCs.

2021-11-03 | PXD014502 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data