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ORC1 binds to cis-transcribed RNAs for efficient activation of human origins

ABSTRACT: ORC1 binds to cis-transcribed RNAs for efficient activation of human origins

PROVIDER: PRJNA725544 | ENA |

REPOSITORIES: ENA

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Dataset's files

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			Action	DRS
	SRR14336648.fastq.gz	Fastqsanger.gz
	SRR14336649.fastq.gz	Fastqsanger.gz
	SRR14336650.fastq.gz	Fastqsanger.gz
	SRR14336651.fastq.gz	Fastqsanger.gz
	SRR14336652.fastq.gz	Fastqsanger.gz

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ORC1 binds to cis-transcribed RNAs for efficient activation of human origins [SNSseq]

Project description:By investigating the RNA binding activity of human ORC1, we show that it interacts with RNAs transcribed at active origins, which is linked to ORC1 dynamic association to the chromatin and optimal origin firing in S phase.

2023-06-05 | GSE173451 | GEO