Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

ABSTRACT: iPSC Retinal Pigmented Epithelium short and long read sequencing

PROVIDER: PRJNA726583 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR14372071_1.fastq.gz	Fastqsanger.gz
	SRR14372071_2.fastq.gz	Fastqsanger.gz
	SRR14372072_1.fastq.gz	Fastqsanger.gz
	SRR14372072_2.fastq.gz	Fastqsanger.gz
	SRR14372073_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 30

Similar Datasets

Dissecting genetic components associated with eye disease using integrative genomic analysis [ATAC-seq]

Project description:GWAS studies have revealed thousands of variants strongly associated with AMD, yet connecting these variants to their cognate genes has not been explored. In this study we fine-mapped AMD risk loci and examined long-range cis chromatin interactions at essential genes of RPE function and disease-associated variants in iPSC-induced retinal pigmented epithelium (RPE) and primary RPE.

2022-04-30 | GSE201677 | GEO

Dissecting genetic components associated with eye disease using integrative genomic analysis [ChIP-seq]

2022-04-30 | GSE201679 | GEO

Dissecting genetic components associated with eye disease using integrative genomic analysis [RNA-seq]

2022-04-30 | GSE201680 | GEO

Dissecting genetic components associated with eye disease using integrative genomic analysis [Capture HiC]

2022-04-30 | GSE201678 | GEO

mouse RPE/choroid age comparison - ATLAS arrays

Project description:Young mice were compared to old mice (2 month vs 24 month) to determine gene changes that occur with aging in the mouse retinal pigmented epithelium/choroid of the eye. Keywords = retinal pigmented epithelium Keywords = aging Keywords = choroid

2010-06-05 | E-GEOD-565 | biostudies-arrayexpress

Expression data of human neuroblastoma cell lines

Project description:Human neuroblatoma cell lines (N=25) and retinal pigmented epithelium cell lines (N=4) were analyzed for gene expression under untreated/baseline growth conditions. Expression profiling and characterization of a set of Neuroblastoma and retinal pigmented epithelium cell lines

2016-02-19 | E-GEOD-78061 | biostudies-arrayexpress

mouse RPE/choroid age comparison - ATLAS arrays

2003-09-30 | GSE565 | GEO

Global gene expression analysis of human iPSC-derived Retinal Pigmented Epithelial (RPE) cells from LCA patients and unaffected persons

Project description:Our purpose was to investigate genes and molecular mechanisms involved in patients with Leber congenital amaurosis (LCA). Fibroblasts from two unrelated clinically-identified patients (Coriell) were reprogrammed to pluripotency by retroviral transduction. These human induced Pluripotent Stem Cells (hiPSCs) were differentiated into neural stem cells (NSC) that mimicked the neural tube stage and retinal pigmented epithelial (RPE) cells that could be targeted by the disease. A genome wide transcriptome analysis was performed with Affymetrix Exon Array GeneChipM-BM-., comparing LCA-hiPSCs derivatives to controls. The aim was to identify differentially expressed genes which may be associated with early developmental defect before the establishment of mature retinal circuitry. We analyzed iPSC-derived retinal pigmented epithelial (RPE) cells from LCA patient's fibroblast (n=2) and iPSC-derivedretinal pigmented epithelial (RPE) cells from healthy people fibroblast (n=2). A total of 13 samples were analyzed : 9 RPE cells derived from iPSC LCA and 4 RPE cells derived from wild-type iPSC.

2015-01-21 | E-GEOD-43926 | biostudies-arrayexpress

Characterization of Stem-cell derived Retinal Pigmented Epithelium (RPE)

Project description:To assess the geome-wide similarities between primary fetal retinal pigmented epithelium (RPE) and stem-cell derived RPE, we performed whole genome microarray expression on primary RPE and both embryonic stem cell (ESC) derived RPE and induced pluripotent stem cell (iPSC) derived RPE. We found ES-derived RPE better resembles fetal RPE than iPS-derived RPE.

2010-11-10 | GSE25143 | GEO

Characterization of Anatomical, Macromolecular, and Gene Expression Changes in the Retinal and Retinal Pigmented Epithelium of the nm3342 Mouse: A Potential Model of Serous Retinal Detachment

Project description:To characterize gene expression changes in mice following serous retinal detachments, we employed whole genome microarray expression profiling as a tool to identify genes with the potential effects on the neural retina as well as retinal pigmented epithelium. Total RNA was harvested from nm3342 (mutant) and age-matched wild-type (C57Bl/6J) mice at P30 or P365 for examination using microarray analysis. Retinas and retinal pigmented epithelium was harvested from both age-matched mutant and wild-type mice.

2015-05-16 | E-GEOD-68961 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data