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10x Single-cell Gene expression analysis of pMHC-NP-induced Tet+ cells and anti-CD3-induced IL-10-producing cells

ABSTRACT: 10x Single-cell Gene expression analysis of pMHC-NP-induced Tet+ cells and anti-CD3-induced IL-10-producing cells

PROVIDER: PRJNA727604 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14436629_1.fastq.gz	Fastqsanger.gz
	SRR14436629_2.fastq.gz	Fastqsanger.gz
	SRR14436630_1.fastq.gz	Fastqsanger.gz
	SRR14436630_2.fastq.gz	Fastqsanger.gz
	SRR14436631_1.fastq.gz	Fastqsanger.gz

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10x Single-cell Gene expression analysis of pMHC-NP-induced Tet+ cells and anti-CD3-induced IL-10-producing cells

Project description:To further explore the transcriptional homogeneity of Tet+ cells with high numbers, we performed scRNAseq of FACS-sorted BDC2.5mi/IAg7 and InsB13-21/IAg7 Tet+ and Tconv cells from pMHCII-NP-treated animals, using the 10x Genomics platform. To study the effect of Bcl6-KO, we also studied transcriptional differences between WT and Bcl6-KO a-CD3-induced IL-10-producing T cells

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