Project description:This petrographic database is a compilation made to study the Oligocene-Langhian succession of the Arquata Scrivia area, consisting of different shallow to deep-water marine sedimentary units deposited in the eastern Tertiary Piedmont Basin (NW Italy). This database is unique for the studied succession, which was not priorly investigated for the petrographic content of its component units. The samples were collected from lower, middle and upper parts of each sedimentary unit and analyzed for identifying their petrographic composition via qualitative and quantitative methods by means of polarized-light microscope. The collected petrographic data are presented within quartz-feldspar-lithic ternary plots. Even though these data are elementary analytical outputs, they represent the starting point for future analyses in order to understand the evolution of the basin on a larger scale.
Project description:This study aims to investigate the DNA methylation patterns at transcription factor binding regions and their evolutionary conservation with respect to binding activity divergence. We combined newly generated bisulfite-sequencing experiments in livers of five mammals (human, macaque, mouse, rat and dog) and matched publicly available ChIP-sequencing data for five transcription factors (CEBPA, HNF4a, CTCF, ONECUT1 and FOXA1). To study the chromatin contexts of TF binding subjected to distinct evolutionary pressures, we integrated publicly available active promoter, active enhancer and primed enhancer calls determined by profiling genome wide patterns of H3K27ac, H3K4me3 and H3K4me1.