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RNA- and ATAC-seq data from hESCs differentiated with Wnt and Activin with or without CPI-203

ABSTRACT: RNA- and ATAC-seq data from hESCs differentiated with Wnt and Activin with or without CPI-203

PROVIDER: PRJNA735402 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR14740635.fastq.gz	Fastqsanger.gz
	SRR14740636.fastq.gz	Fastqsanger.gz
	SRR14740637.fastq.gz	Fastqsanger.gz
	SRR14740638.fastq.gz	Fastqsanger.gz
	SRR14740639.fastq.gz	Fastqsanger.gz

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RNA- and ATAC-seq data from hESCs differentiated with Wnt and Activin with or without CPI-203

Project description:We report genome-wide changes in chromatin state and transcriptional output following Wnt-priming and subsequent Activin induced differentiation of human embryonic stem cell and the effects of BET bromodomain inhibition during Wnt-priming. The two signals, Wnt and Activin, although provided sequentially, result in stable mesendoderm differentiation (Yoney et al., 2018).

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