Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Gene expression changes in REH following STAT3 inhibition by shRNA

ABSTRACT: Gene expression changes in REH following STAT3 inhibition by shRNA

PROVIDER: PRJNA743292 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15023657_1.fastq.gz	Fastqsanger.gz
	SRR15023657_2.fastq.gz	Fastqsanger.gz
	SRR15023658_1.fastq.gz	Fastqsanger.gz
	SRR15023658_2.fastq.gz	Fastqsanger.gz
	SRR15023659_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 12

Similar Datasets

Gene expression changes in REH following STAT3 inhibition by shRNA

Project description:STAT3 (Signal transducer and activator of transcription 3) expression is associated with with t(12;21) acute lymphoblastic leukaemia (ALL) and it is crucial for the survival of the t(12;21) ALL . Our study investigated the STAT3 regulated pathways and discovered a novel STAT3-TP53 axis in B-ALL. In order to determine the STAT3 regulated pathways in t(12;21) ALL cells, we performed RNAseq analysis on the Pre-B Acute Lymphoblastic Leukemia (ALL) cell line REH following shRNA-mediated STAT3 knockdown

2024-01-31 | GSE179332 | GEO

Gene expression changes in REH following STAT3 pharmacological inhibition

Project description:Gene expression changes in REH following STAT3 pharmacological inhibition

| PRJNA743296 | ENA

Gene expression changes in REH following STAT3 pharmacological inhibition

2024-01-31 | GSE179333 | GEO

Gene expression changes in REH following CDC42 inhibition

Project description:Gene expression changes in REH following CDC42 inhibition

| PRJNA640612 | ENA

Expression analysis of Reh cells after transfection with shRNA targeting CBFA2T3 and/or constitutively active IKKβ(EE)

Project description:Genome-wide gene expression analysis of Reh cells following transfection with shRNA targeting CBFA2T3, constitutively active IKKβ(EE), or both in combination.

2010-04-23 | GSE20115 | GEO

Expression analysis of Reh cells after transfection with shRNA targeting CBFA2T3 and/or constitutively active IKKÎ²(EE)

Project description:Genome-wide gene expression analysis of Reh cells following transfection with shRNA targeting CBFA2T3, constitutively active IKKÎ²(EE), or both in combination. Affymetrix U133 Plus 2.0 oligonucleotide arrays were hybridized to determine the gene expression profile of acute lymphoblastic leukemia-derived Reh cells following transfection with i) control shRNA construct, ii) shRNA construct targeting CBFA2T3, iii) a constitutively active variant of the IkB kinase Î² (IKKÎ²(EE)), or iv) shRNA targeting CBFA2T3 in combination with IKKÎ²(EE). All hybridizations were done in biological duplicates.

2010-05-07 | E-GEOD-20115 | biostudies-arrayexpress

Gene expression changes in REH following CDC42 inhibition

Project description:ARHGEF4 expression is associated with t(12;21) acute lymphoblastic leukaemia (ALL). Our study investigated the substrate specificity of ARHGEF4, a member of the diffuse B-cell lymphoma (DBL) family of guanine nucleotide exchange factors (GEFs), in t(12;21) ALL REH cells. ARHGEF4 was found to activate the small guanine nucleotide binding protein (GTPase) CDC42. In order to determine the function of CDC42 in t(12;21) ALL cells, we performed RNAseq analysis on REH cells treated for 24 hours with DMSO vehicle control in comparison to 25uM ML141, a CDC42 inhibitor.

2020-06-20 | GSE152836 | GEO

RNA-seq following shRNA-mediated knock-down of ETV6-RUNX1 in the B-ALL cell line Reh

Project description:RNA-seq following shRNA-mediated knock-down of ETV6-RUNX1 in the B-ALL cell line Reh

| PRJEB44088 | ENA

Combined MEK and JAK/STAT3 pathway inhibition effectively decreases medulloblastoma tumor progression.

Project description:RNA sequencing was carried out to identify the signaling pathways and hallmarks that change following MEK and/or JAK/STAT3 pathway inhibition.

2022-07-04 | GSE165960 | GEO

Homo sapiens isolate:REH

Project description:REH MultiOmics

| PRJNA600820 | ENA