Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Inter-species comparison of little skate motor neuron gene expression with chick and mouse

ABSTRACT: Inter-species comparison of little skate motor neuron gene expression with chick and mouse

PROVIDER: PRJNA747908 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15185978_1.fastq.gz	Fastqsanger.gz
	SRR15185978_2.fastq.gz	Fastqsanger.gz
	SRR15185979_1.fastq.gz	Fastqsanger.gz
	SRR15185979_2.fastq.gz	Fastqsanger.gz
	SRR15185980_1.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 22

Similar Datasets

Inter-species comparison of little skate motor neuron gene expression with chick and mouse

Project description:The little skate, a cartilaginous fish evolutionarily distal from tetrapods, displays walking-like behavior and has conserved genetic programs and neuronal substrates for land-walking. Studies on little skate have been limited due to lack of high-quality genome assembly. Here, we generated an improved genome assembly of little skate reflecting precise gene annotation and structures and performed integrated analysis of gene expression and chromatin accessibility to investigate molecular mechanisms of fin motor neuron development. Through interspecies comparison of RNA expression, common and species-specific genes expressed in fin/limb/wing level motor neurons were identified. Moreover, by performing chromatin accessibility analysis with a pure fin motor neuron population the potential regulators controlling the gene expression in fin motor neurons were identified. Interspecies comparison of genomic data, gene expression, and chromatin accessibility assay suggest that the little skate has highly conserved gene regulatory mechanisms controlling tetrapod locomotion, which was not previously expected.

2022-10-24 | GSE180336 | GEO

little skate motor neuron

Project description:little skate motor neuron

| PRJNA747902 | ENA

Genome-wide screening of gene regulation of little skate motor neuron

2022-10-24 | GSE180334 | GEO

Genome-wide screening of gene regulation of little skate motor neuron

Project description:Genome-wide screening of gene regulation of little skate motor neuron

| PRJNA747898 | ENA

Base-resolution DNA methylation maps of little skate (Leucoraja erinacea)

Project description:Using MetylC-seq we investigated single-base resolution methylomes of embryonic and adult pelvic and pectoral fins of little skate.

2022-12-31 | GSE190730 | GEO

The little skate genome and the evolutionary emergence of wing-like fin appendages [Hi-C Skate stage 31]

Project description:While retaining ancestral morphological and genomic traits, skates evolved a novel body plan with remarkably enlarged wing-like fins that allowed skates to thrive in benthic environments, but their molecular underpinnings remain elusive. Here we investigate the origin of this phenotypical innovation by assembling a high-quality chromosome-scale genome sequence for the little skate Leucoraja erinacea and by generating extensive regulatory profiling datasets in developing fins (gene expression, chromatin occupancy and conformation). We show that despite their derived morphology, the skate genome retains multiple features of the ancestral jawed vertebrate genome.

2023-01-12 | GSE217073 | GEO

The little skate genome and the evolutionary emergence of wing-like fin appendages [HiChIP]

2023-01-12 | GSE188976 | GEO

The synarcual of the little skate: Novel development among the vertebrates

Project description:The synarcual is a specialized adaptation of the anterior axial skeleton comprising a putatively fused array of vertebral elements characteristic of jawed vertebrate (gnathostome) clades such as batoid and chimaeroid chondrichthyans, as well as a fossil group known as the placoderms. Placoderms represent the phylogenetically most basal jawed vertebrates and the presence of a synarcual in these and chondrichthyans may suggest a conserved vertebral type for jawed vertebrates, predating the divergence of stem and crown gnathostomes. Alternatively, synarcuals may have evolved independently in these lineages, exhibiting a remarkable case of morphological convergence. We investigated the early development of the cervicothoracic synarcual of an emerging model chondrichthyan, the Little skate Leucoraja erinacea, by combining x-ray computed tomography, classical histology, and a de novo transcriptome assembly for two developmental stages of the skate synarcual and post-synarcual axial skeletal elements.

2019-06-01 | GSE121572 | GEO