Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The differencial expression of cardiac-specific NPRA-deficient mice compares to wild type.

ABSTRACT: The differencial expression of cardiac-specific NPRA-deficient mice compares to wild type.

PROVIDER: PRJNA750769 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Similar Datasets

The differencial expression of cardiac-specific NPRA-deficient mice compares to wild type.

Project description:To investigate the altered methylation cardiac-specific NPRA-deficient mice compares to wild type, methylation level alterations were detected by Arraystar Mouse m6A Single Nucleotide resolution microarray analysis (mazF-RIP) using the myocardium from NPRA-deficient (NPRA-/-) mice and wild-type (NPRA+/+) mice as control.

2022-07-01 | GSE181128 | GEO

The methylation level alterations from cardiac-specific NPRA-deficient mice.

2022-07-01 | GSE181039 | GEO

The methylation level alterations from cardiac-specific NPRA-deficient mice.

Project description:The methylation level alterations from cardiac-specific NPRA-deficient mice.

| PRJNA750459 | ENA

Transcription profiling of skeletal and cardiac muscles in dysferlin-deficient SJL/J mice and wild type mice to understand the protective mechanisms against dysferlin deficiency in cardiac muscles.

Project description:Dysferlin is expressed in skeletal and cardiac muscle. However, dysferlin deficiency, namely limb girdle muscular dystrophy 2B (LGMD2B) and Myoshi myopathy, results in skeletal muscle weakness and spares the heart. This dichotomy could be caused by differential regulation of protective mechanisms. Therefore, we compared intraindividual mRNA expression profiles between cardiac and skeletal muscle in dysferlin-deficient SJL/J mice and normal C57BL/6 mice. Experiment Overall Design: 20 chips were analyzed. They represent 4 groups of 5 replicates each. Experiment Overall Design: The 4 groups are cardiac (LV) and skeletal muscle of normal and dysferlin deficient mice. Experiment Overall Design: Tissues from normal mice are the controls in comparison to tissues of dysferlin deficient mice.

2007-09-04 | E-GEOD-2507 | biostudies-arrayexpress

Activin-deficient granulosa cells

Project description:Compares activin deficient granulosa cells (Inhba flox/-; Inhbb-/-; Amhr2cre/+) to wild type granulosa cells Keywords: Genetic Modificaton

2007-12-28 | GSE7150 | GEO

Transcription profiling of mouse Inhba flox/- Inhbb-/- Amhr2cre/+ activin-deficient granulosa cells vs. wild type

Project description:Compares activin deficient granulosa cells (Inhba flox/-; Inhbb-/-; Amhr2cre/+) to wild type granulosa cells Experiment Overall Design: Three replicate wild type granulosa cell samples compared to 2 activin-deficient granulosa cell samples. Each replicate is derived from 2-3 females.

2008-06-15 | E-GEOD-7150 | biostudies-arrayexpress

Cardiac and skeletal muscle gene expression profiles in dysferlin deficient mice

2005-07-10 | GSE2507 | GEO

Expression data from 7-month-old mdx mouse hearts wild-type and deficient for cardiomyocyte-specific IKKβ

Project description:We found genetic deletion of IKKβ in mdx cardiomyocytes improved cardiac function and normalized calcium transients. We used microarrays to profile gene expression in hearts of mdx mice with intact IKKβ signaling and hearts of mdx mice with IKKβ-deficient cardiomyocytes to identify genes differentially regulated by NF-[kappa]B. signaling in dystrophic hearts.

2018-06-14 | GSE114025 | GEO

Comparative cardiac induction time-courses using wild-type or genetically modified human embryonic stem cells

Project description:This study compares directed cardiac differentiation time-courses using (i) HuES6 cells with endogenous ISL1 knockout + inducible ISL1 transgene, and (ii) wild-type HuES6 cells. For the first series, a subset of samples was left untreated (= ISL1 knockout scenario) while another subset received doxycycline treatment to upregulate ISL1 at days 3 and 4 of differentiation (ISL1 rescue). For the second series, a subset of samples was differentiated under default conditions (no RA) while another subset received retinoic acid (RA) on days 3 and 4 of differentiation, which leads to an atrial-like phenotype.

2018-01-13 | GSE100592 | GEO

RNA-seq data: Baf60c homozygous deletion vs. WT at two time points in cardiac differentiation

Project description:This project compares Baf60c homozygous deletions to WT at two time points during cardiac differentiation. This data is used in two separate projects: first to assess the role of Baf60c in regulating cardiac gene expression, and second to assess the repeatability of results from different RNA-seq analysis tools.

2014-08-10 | GSE59383 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data