Project description:We looked for difference in genetic expression in 4 cell lines that have the same genetic background but reproduce breast cancer progression. Especially, we identied genes that were overexpressed in late cancer progression (MCFT1 and MCFCA1) but not in early stages (MCF10A and MCFNeoT).
Project description:miRNA expression is often disregulated in cancer pathways, such as progression of resistance. We used microarrays in order to determine the differences in miRNA expression between breast cancer cell lines and their resistant pairs.
Project description:TMT16 plex MS proteomics based comparison of 8 breast cancer cell lines in duplicates. Peptides were fractionated by HiRIEF and analyzed by Q-exactive HF.
The cell lines are: HCC1937
MDAMB453
SUM185PE
MDAMB468
BT549
HCC1599
HCC2157
MDAMB231