Project description:To investigate the effect of Progranulin on neutrophils phagocytosis and killing of Candida albicans, we designed RNA-Seq analysis of wild-type and PGRN-/- neutrophils challenged with Candida albicans in vitro at one time point.
Project description:To investigate the effect of progranulin on macrophages phagocytosis and killing of Candida albicans, we designed RNA-Seq analysis of wild-type and PGRN-/- macrophages challenged with Candida albicans in vitro at one time point.
Project description:The antifungal activity of aurones SH1009 and SH9051 against Candida albicans was investigated. A whole-genome transcriptional analysis post aurone SH1009 and SH9051 treatments on the C. albicans SC5314 strain was performed using RNA-seq technique.