Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Dysregulated Genes, Biological pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A preliminary analysis

ABSTRACT: Dysregulated Genes, Biological pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A preliminary analysis

PROVIDER: PRJNA753866 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15418943.fastq.gz	Fastqsanger.gz
	SRR15418944_1.fastq.gz	Fastqsanger.gz
	SRR15418944_2.fastq.gz	Fastqsanger.gz
	SRR15418945_1.fastq.gz	Fastqsanger.gz
	SRR15418945_2.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 37

Similar Datasets

Dysregulated Genes, Biological pathways, and Gastrocnemius Muscle Fiber Types Associated With Progression of Peripheral Artery Disease: A preliminary analysis

Project description:We report the differentially expressed genes among people with PAD Progression, PAD no progression compared to non-PAD.

2023-03-14 | GSE181930 | GEO

Single Nuclei RNA Sequencing of the Gastrocnemius Muscle Reveals Unique Transcriptomic Signatures of Peripheral Artery Disease

Project description:This study examines the transcriptional profile at the single-nuclei resolution human gastrocnemius skeletal muscle from 20 patients with Peripheral artery disease (PAD) and 12 non-PAD controls. In all libraries, muscle specimens were pooled prior to nuclei isolations were performed.

2023-10-10 | GSE233882 | GEO

Single Nuclei RNA Sequencing of the Gastrocnemius Muscle Reveals Unique Transcriptomic Signatures of Peripheral Artery Disease

Project description:Single Nuclei RNA Sequencing of the Gastrocnemius Muscle Reveals Unique Transcriptomic Signatures of Peripheral Artery Disease

| PRJNA978497 | ENA

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Project description:Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

| PRJEB28447 | ENA

Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

Project description:Dysregulated Microbial Fermentation of Soluble Fiber Induces Cholestatic Liver Cancer

| PRJEB28449 | ENA

Gene expression profiling of gastrocnemius of mini muscle mice

Project description:Few studies have investigated heterogeneity of selection response in replicate lines subjected to equivalent selection. We developed 4 replicate lines of mice based on high levels of voluntary wheel running (high runner or HR lines) while also maintaining 4 non-selected control lines. This led to the unexpected discovery of the HR mini-muscle (HRmini) phenotype, recognized by a 50% reduction in hindlimb muscle mass, which became fixed in 1 of the 4 HR selected lines. Here, we report genome-wide expression profiling describing transcriptome differences between HRnormal and HRmini medial gastrocnemius. This work provides a resource for understanding differences in muscle phenotypes in populations exhibiting high running capacity. Male mice were used from an animal model of 4 closed lines selectively bred for high voluntary wheel-running behaviour (HR) and 4 control lines bred without intentional selection, described in Swallow et al. Animals used in the current work were sampled from generation 37 at a mean age of 84 days (range = 79-86). For microarray analysis, we used gastrocnemius muscles (including both lateral and medial portions) from HRmini line #3 and HRnormal line #8 (n = 6, in each group). To obtain sufficient RNA, gastrocnemius samples of HRmini were pooled from left and right limbs from each animal, whereas HRnormal gastrocnemius was sampled from either left or right limb only.

2013-02-19 | E-GEOD-41910 | biostudies-arrayexpress

microRNA counts from gastrocnemius medialis (ENCSR655NLY)

Project description:microRNA counts from gastrocnemius medialis (ENCSR655NLY)

| PRJNA909660 | ENA

microRNA counts from gastrocnemius medialis (ENCSR505IZZ)

Project description:microRNA counts from gastrocnemius medialis (ENCSR505IZZ)

| PRJNA909704 | ENA

Pulmonary artery banded rat heart

Project description:Changes in juvenile rat heart with pulmonary artery banding

2022-05-20 | PXD027427 | Pride

Matrisome age-related changes in the mouse gastrocnemius muscle

Project description:In recent years, thanks to the great development of mass spectrometry (MS)-based high-throughput proteomic techniques, a large-scale protein characterization is less challenging. Proteomic approaches have been successfully applied to SM in different experimental models [21–24]; however, to date, there is little information on ECM proteins and how they change during ageing. The identification and quantification of ECM components and their interactions are es-sential steps to understand the role of the matrisome in sarcopenia. In this context, we combined a proteomic approach (i.e., LC-MS/MS and bioinformatic analyses) with mor-phological and morphometrical evaluations at fluorescence and transmission electron microscopy of the gastrocnemius muscle in adult and old mice. This age range has been selected since it has been observed that most of changes in muscle protein expression take place after middle age. The gastrocnemius muscle was selected for analysis since it is prevalently composed of fast-twitch fibre, which are especially affected by atrophy during aging. Our findings highlighted several modifications of ECM protein composition and organization in old mice, which likely play a role in the alteration of muscle properties during aging.

2022-02-17 | PXD027895 | Pride

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data