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RNA sequencing analysis of human glioblastoma cell line U87MG treated with LMO2 overexpression.

ABSTRACT: RNA sequencing analysis of human glioblastoma cell line U87MG treated with LMO2 overexpression.

PROVIDER: PRJNA755253 | ENA |

REPOSITORIES: ENA

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			Action	DRS
	SRR15466605_1.fastq.gz	Fastqsanger.gz
	SRR15466606_1.fastq.gz	Fastqsanger.gz
	SRR15466607_1.fastq.gz	Fastqsanger.gz
	SRR15466608_1.fastq.gz	Fastqsanger.gz
	SRR15466609_1.fastq.gz	Fastqsanger.gz

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Similar Datasets

RNA sequencing analysis of human glioblastoma cell line U87MG treated with LMO2 overexpression.

Project description:To understand the changes in the expression of genes in U87MG cells due to LMO2, we analyzed the transcriptome of U87MG cells overexpressing LMO2. As a result, we identify differentially expressed genes patterns so that the signaling mechanism regulated by LMO2 in GBM and changes in cells were observed. These RNA sequencing analysis results enable an understanding of the signaling mechanism by LMO2 in GBM.

2022-07-13 | GSE182169 | GEO

Human LMO2 binding protein LC-MSMS in U87MG(Glioblastoma cell)

Project description:To identify the binding partner of LMO2 for explanation of STAT3 signal-related protein in human glioblastoma

2022-08-11 | PXD028254 | Pride

Gene expression data in U87MG cell line transfected with miR-490 overexpression vector PC-490 or its control PCDNA3.1 (+).

Project description:miR-490 is robustly downregulated in GBM tumour samples. This study identifies the genes differentially expressed upon miR-490 overexpression in U87MG glioblastoma cell line. GeneChip PrimeView Human Gene Expression Array was used to assess mRNA expression profile in response to miR-490 overexpression in U87MG cell line.

2018-08-24 | GSE118983 | GEO

Gene expression data in U87MG cell line transfected with NeuroD2-overexpression and control vector

Project description:NeuroD2 is downregulated in glioblastoma (GBM) tumor samples. The study identifies the genes regulated by NeuroD2 in GBM cell lines grown under hypoxia We used human primeview gene expression microarray chips to assess the mRNA expression profile in response to NeuroD2 overexpression in U87MG cells under hypoxic microenvironment.

2018-03-01 | GSE96911 | GEO

Establishment of radioresistant U87MG glioblastoma cell line

Project description:Establishment of radioresistant U87MG glioblastoma cell line

| PRJNA853300 | ENA

Establishment of radioresistant U87MG glioblastoma cell line

Project description:To explore factors contributing to radioresistance in GBM, we established GBM radioresistant cell line using U87MG human GBM cells.

2022-06-29 | GSE207002 | GEO

Transcription profiling array of human glioblastoma cell line U87MG comparing control cells (U87RNAi) with U87shLAPTM5 knockdown cells

Project description:After performing an in-vivo screening with U87 glioblastoma cells transduced with a knockdown library several genes could be identified. LAPTM5 which was one of the candidates was further evaluated. Single knockdown of LAPTM5 in U87MG conferred a pro-invasive phenotype in-vitro and in-vivo. To decipher the underlying pathways U87MG control cells (U87RNAi) and U87shLAPTM5 were analyzed after in-vitro culture by a transcription profiling Array.

2017-12-07 | E-MTAB-6316 | biostudies-arrayexpress

Transcriptome analysis of CD133 overexpressed U87MG glioblastoma cells

Project description:This study investigated the biological function of CD133 by ectopic expression of CD133 in U87MG cell line. Although CD133 is widely used as a cancer stem cell marker, there are a few studies that examined its own biological functions. While a number of loss-of-function studies about CD133 have shown that CD133 have effects on cancer progression, there are few gain-of-function studies about functions of CD133. Thus, we identified the potential function of CD133 by its overexpression in U87MG glioblastoma cell line. Though there were no significant changes in cell growth and sphere forming ability, elevated IL-1β and its downstream chemokines (CCL3, CXCL3, CXCL5) may function as chemoattractants which affect recruitment of Ly6G+ neutrophils surrounding necrotic regions in vivo and migration of neutrophil-like dHL-60 cells. Taken together, this results imply that CD133 can regulate IL-1β signaling, and promotes the environmental change.

2017-08-03 | GSE99385 | GEO

mRNA expression profiling (QuantSeq3' mRNA) analysis of human glioblastoma cell line U87MG treated with ID Family (ID1, ID2, ID3, and ID4) overexpression

Project description:To understand the changes in the expression of genes in U87MG cells due to ID Family, we analyzed the transcriptome of U87MG cells overexpressing ID Family. As a result, we identify differentially expressed genes patterns so that the signaling mechanism regulated by ID Family in GBM and changes in cells were observed. These mRNA expression profiling analysis results enable an understanding of the signaling mechanism by ID Family in GBM.

2022-07-13 | GSE182670 | GEO

Expression data from U87MG subclones

Project description:U87MG is a glioblastoma cell line that shows substantial heterogeneity despite long-term passaging. We used microarrays to identify variations in gene expression that are associated with phenotypic differences among subclones derived from U87MG.

2015-02-12 | GSE54967 | GEO

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