Project description:we profiled whole transcriptome in depression patients’ and healthy volunteers blood samples via microarray analysis.Differentially expressed circRNAs, lncRNAs and mRNAs were selected for deep analysis. Especially the Differentially expressed genes that associated with cancer
Project description:we profiled whole transcriptome in depression patients’ and healthy volunteers blood samples via microarray analysis.Differentially expressed miRNAs were selected for deep analysis. Especially the Differentially expressed genes that associated with cancer
Project description:To identify early predictive biomarkers for postpartum depression using peripheral blood gene expression profiles RNA was isolated from peripheral blood collected in Tempus RNA tubes (Applied Biosystems, Darmstadt, Germany) at all three investigated time points for each woman in the discovery sample. RNA was isolated using the Versagene kit (Gentra Systems, Minneapolis, U.S.A.), quantified using the Nanophotometer and quality checks were performed on the Agilent Bioanalyzer.
Project description:Blood samples taken from healthy controls and patients with major depression were analyzed for differences in microRNA expression. Patients were treated with either electroconvulsive therapy or ketamine and samples were again analyzed to determine if these treatments affected microRNA expression. Baseline microRNA expression profiles were studied to see if they could predict treatment response.