Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Single-cell RNA-Seq of Foxe1KO mouse ESC-derived cells

ABSTRACT: Single-cell RNA-Seq of Foxe1KO mouse ESC-derived cells

PROVIDER: PRJNA755901 | ENA |

REPOSITORIES: ENA

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
	SRR15508402.fastq.gz	Fastqsanger.gz
	SRR15508403.fastq.gz	Fastqsanger.gz
	SRR15508404.fastq.gz	Fastqsanger.gz
	SRR15508405.fastq.gz	Fastqsanger.gz
	SRR15508406.fastq.gz	Fastqsanger.gz

Items per page:

1 - 5 of 8

Similar Datasets

Single cell RNA seq of micropatterns derived from Human ESC Micropatterns

Project description:Single cell RNA seq of micropatterns derived from Human ESC Micropatterns

| PRJNA1175627 | ENA

Comparison of ESC-derived and Primary-derived Tip-like Cell Transplants

Project description:Comparison of ESC-derived and Primary-derived Tip-like Cell Transplants

| PRJNA941344 | ENA

Mouse ESC-derived NSPCs NFIA OE (miRNA)

Project description:Since the NFI transcription factors have been shown to be key regulators of gliogenesis, we utilized this pathway to identify miRNAs involved in the regulation of the neurogenesis-to-gliogenesis switch by neural stem/progenitor cells (NSPCs). We focused on miRNAs with expression levels that were differentially regulated downstream of NFIA, and established a mouse embryonic stem cell (ESC) line that expresses NFIA in a doxycycline (Dox)-dependent manner. NFIA-overexpressing (OE) and control NSPCs (neurospheres) derived from ESCs were purified from their mixed cultures (primary neursphsres (PNs) or secondary neurospheres (SNs) ) by fluorescence activated cell sorting and subjected to miRNAarray analysis.

2015-08-01 | E-GEOD-70128 | biostudies-arrayexpress

Subcellular proteomics of murine ESC-derived neurons

Project description:We studied the effects of different stimuli on on the subcellular proteome of neurons differentiated from murine embryonic stem cells (ESC). We focused on the changes in the chromatin-bound fraction to elucidate specific differences in the gene regulatory machinery activated upon stimulation with Brain-derived neurotrophic factor (BDNF) or a general membrane-depolarization stimulus, potassium chloride (KCl).

2022-09-15 | PXD022378 | Pride

Bulk RNA-Seq of Foxe1KO and control Nkx2-1/mKO2+ mouse ESC-derived cells

Project description:Bulk RNA-Seq of Foxe1KO and control Nkx2-1/mKO2+ mouse ESC-derived cells

| PRJNA756366 | ENA

Comparison of ESC-derived and Primary-derived Tip-like Cell Transplants

Project description:The goal of this experiment was to determine whether transcriptionally similar ESC-derived and primary donor cells give rise to similar donor-derived cells following transplantation into bleomycin injured lungs.

2023-08-24 | GSE226761 | GEO

Mouse ESC-derived NSPCs NFIA OE (GE)

2015-08-01 | E-GEOD-70130 | biostudies-arrayexpress

Population RNA-seq of human ESC-derived cardiac derivatives

Project description:Population RNA-seq of human ESC-derived cardiac derivatives

| PRJEB30993 | ENA

Novel DNA modification in mouse ESC

Project description:Novel DNA modification in mouse ESC

| PRJNA292541 | ENA

Notch Activation Confers Enhanced Lymphoid Potential in Murine ESC/iPSC-derived HSC and Reconstitutes Adaptive Immunity In Vivo [RNA-Seq]

Project description:Hematopoietic stem cell (HSC) transplantation has the potential to cure blood disorders but is limited by donor availability. Hence innovative approaches to engineer HSC are critically needed. HoxB4 over-expression in mouse embryonic stem cell-derived HSC (ESC-HSC) confers long-term engraftment, yet lacks efficient lymphogenesis. Transcriptome comparison of ESC-HSC versus embryo-derived HSC showed that ESC-HSC are deficient in expression programs activated by Notch. Therefore, we aim to improve ESC-HSC by further providing Notch signals through Notch1 intra-cellular domain transgene activation or by ligand stimulation. Here, we report that Notch-enhanced ESC-HSC (nESC-HSC) confer clonal multipotentiality with robust lymphopoiesis that endows adaptive immunity. Notably, nESC-HSC further evolve to a hybrid cell-type co-expressing gene regulatory networks of hematopoietic stem/progenitor cells and differentiated lineages at single-cell level that accounts for multipotentiality. Our work reveals a proof-of-concept model of HSC engineering by assembling self-renewing factor and lineage-guiding pathway into one product-cell that functionally recapitulate HSC in vivo.

2016-12-21 | GSE71794 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data